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PMID: 2065661 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The ribosomal protein L2 in S. cerevisiae controls the level of accumulation of its own mRNA.

The EMBO journal ·Vol. 10 ·No. 8 ·1991-08-00 ·Pages 2215-21

Presutti C, Ciafré SA, Bozzoni I

Abstract

The expression of the yeast L2 r-protein gene is controlled at the level of mRNA accumulation. The product of the gene appears to participate in this regulation by an autogenous feedback mechanism. This control does not operate at the level of transcription but instead affects L2 mRNA accumulation. This autogenous regulation of mRNA accumulation provides an interesting analogy to the autogenous translational regulation of r-proteins in Escherichia coli.

MeSH Terms
Blotting, Northern Blotting, Southern DNA, Fungal/genetics Gene Expression Regulation, Fungal Plasmids RNA Processing, Post-Transcriptional RNA, Fungal/genetics,metabolism RNA, Messenger/genetics,metabolism Ribosomal Proteins/genetics,metabolism Saccharomyces cerevisiae/metabolism Transcription, Genetic
Chemicals
DNA, Fungal RNA, Fungal RNA, Messenger Ribosomal Proteins ribosomal protein L2
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Presutti C
Department of Genetics and Molecular Biology, University La Sapienza, Rome, Italy.
Ciafré S A
Bozzoni I
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37 references, click to expand
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Article Info
Journal
The EMBO journal
Abbr.
EMBO J
ISSN
0261-4189
Published
1991-08-00
Pages
2215-21
Language
English
Region
England
NLM ID
8208664
PMCID
PMC452910
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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