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PMID: 2157134 Published · ppublish English Journal Article Review

Invertrons, a class of structurally and functionally related genetic elements that includes linear DNA plasmids, transposable elements, and genomes of adeno-type viruses.

Microbiological reviews ·Vol. 54 ·No. 1 ·1990-03-00 ·Pages 66-74

Sakaguchi K

Abstract

Invertrons are genetic elements composed of DNA with inverted terminal repeats at both ends, covalently bonded to terminal proteins involved in the initiation of DNA replication at both their 5' termini when they exist in the cytoplasm of their host in free form. They function as viruses, linear DNA plasmids, transposable elements, and sometimes combinations of two of these properties. They differ from retroviruses and related retro-type transposons which have direct repeats on both their genomic ends and exploit RNA intermediates for replication of their DNA. A model for replication and integration of invertrons is presented, as well as a model for transposition of transposable elements.

MeSH Terms
Adenoviridae/genetics Bacillus subtilis/genetics Base Sequence DNA Transposable Elements DNA, Bacterial/genetics Molecular Sequence Data Plasmids/genetics Repetitive Sequences, Nucleic Acid
Chemicals
DNA Transposable Elements DNA, Bacterial
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Sakaguchi K
Nihon Shokuhin Kako Laboratories, Tokyo, Japan.
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Article Info
Journal
Microbiological reviews
Abbr.
Microbiol Rev
ISSN
0146-0749
DOI
10.1128/mr.54.1.66-74.1990
Published
1990-03-00
Pages
66-74
Language
English
Region
United States
NLM ID
7806086
PMCID
PMC372759
Subset
IM
External Links
PubMed source DOI: 10.1128/mr.54.1.66-74.1990 PMC Full Text
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