Home LiteratureArticle Details
PMID: 2183788 Published · ppublish English Journal Article Review

Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase.

The Biochemical journal ·Vol. 266 ·No. 3 ·1990-03-15 ·Pages 625-36

Vermeer C

Abstract

暂无摘要

MeSH Terms
1-Carboxyglutamic Acid/metabolism Amino Acid Sequence Animals Carbon-Carbon Ligases Humans Ligases/metabolism Molecular Sequence Data Nutritional Requirements Vitamin K/metabolism
Chemicals
Vitamin K 1-Carboxyglutamic Acid Ligases Carbon-Carbon Ligases glutamyl carboxylase
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Vermeer C
Department of Biochemistry, University of Limburg, Maastricht, The Netherlands.
References (140)
140 references, click to expand
  1. Vitamin K-dependent carboxylation of pulmonary surfactant-associated proteins.
    Proc Natl Acad Sci U S A. 1987 Aug;84(16):5952-6 PMID: 3475711
  2. The in vivo effects of oral anticoagulants in man: comparison between liver and non-hepatic tissues.
    Thromb Haemost. 1988 Apr 8;59(2):147-50 PMID: 3260413
  3. Vitamin K dependent carboxylation of glutamate residues to gamma-carboxyglutamate in microsomes from spleen and testes: comparison with liver, lung, and kidney.
    Biochemistry. 1983 Mar 1;22(5):1077-82 PMID: 6132618
  4. Structure and function of protein C.
    Semin Thromb Hemost. 1984 Apr;10(2):109-21 PMID: 6429858
  5. Urine glycoprotein crystal growth inhibitors. Evidence for a molecular abnormality in calcium oxalate nephrolithiasis.
    J Clin Invest. 1985 Oct;76(4):1455-62 PMID: 4056037
  6. Vitamin K-dependent carboxylase.
    Annu Rev Biochem. 1985;54:459-77 PMID: 3896125
  7. Basic mechanisms in blood coagulation.
    Annu Rev Biochem. 1975;44:799-829 PMID: 237463
  8. Recognition site directing vitamin K-dependent gamma-carboxylation resides on the propeptide of factor IX.
    Cell. 1987 Jan 30;48(2):185-91 PMID: 3802193
  9. Isolation and sequence of the cDNA for human protein S, a regulator of blood coagulation.
    Proc Natl Acad Sci U S A. 1986 Sep;83(18):6716-20 PMID: 2944113
  10. In vitro degradation of bone particles by human monocytes is decreased with the depletion of the vitamin K-dependent bone protein from the matrix.
    Endocrinology. 1986 Apr;118(4):1636-42 PMID: 3512259
  11. Development of the human coagulation system in the full-term infant.
    Blood. 1987 Jul;70(1):165-72 PMID: 3593964
  12. Relationship of dithiothreitol-dependent microsomal vitamin K quinone and vitamin K epoxide reductases inhibition of epoxide reduction by vitamin K quinone.
    Biochim Biophys Acta. 1984 Mar 22;798(1):141-3 PMID: 6704420
  13. A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.
    J Biol Chem. 1976 Jan 25;251(2):355-63 PMID: 1245477
  14. Specific tritium labeling of gamma-carboxyglutamic acid in proteins.
    Biochemistry. 1979 Oct 30;18(22):4992-9 PMID: 508728
  15. Partial sequence of rat prothrombin and the activity of two related pentapeptides as substrates for the vitamin K-dependent carboxylase system.
    FEBS Lett. 1977 Mar 15;75(1):226-30 PMID: 852584
  16. Vitamin K-dependent carboxylation. In vitro modification of synthetic peptides containing the gamma-carboxylation recognition site.
    J Biol Chem. 1989 Aug 25;264(24):14145-50 PMID: 2569466
  17. The mode of action of vitamin K. Identification of gamma-carboxyglutamic acid as a component of prothrombin.
    J Biol Chem. 1974 Oct 10;249(19):6347-50 PMID: 4214105
  18. Studies of the vitamin K-dependent carboxylase and vitamin K epoxide reductase in rat liver.
    Haemostasis. 1986;16(3-4):193-215 PMID: 3530899
  19. The effect of Gla-containing proteins on the precipitation of insoluble salts.
    Biochem Biophys Res Commun. 1987 Jan 15;142(1):113-9 PMID: 3492999
  20. In vitro carboxylation of a blood coagulation factor IX precursor produced by recombinant-DNA technology.
    Thromb Haemost. 1989 Apr 25;61(2):238-42 PMID: 2749597
  21. The role of blood clotting factor V in the conversion of prothrombin and a decarboxy prothrombin into thrombin.
    Biochim Biophys Acta. 1978 Feb 1;538(3):521-33 PMID: 564211
  22. Vitamin K deficiency from dietary vitamin K restriction in humans.
    Am J Clin Nutr. 1988 Mar;47(3):475-80 PMID: 3348159
  23. Reduced thioredoxin: a possible physiological cofactor for vitamin K epoxide reductase. Further support for an active site disulfide.
    Biochem Biophys Res Commun. 1988 Sep 30;155(3):1248-54 PMID: 3140805
  24. Vitamin K-dependent carboxylation. A synthetic peptide based upon the gamma-carboxylation recognition site sequence of the prothrombin propeptide is an active substrate for the carboxylase in vitro.
    J Biol Chem. 1988 Jul 15;263(20):9697-702 PMID: 3133366
  25. Identification of vitamin K-dependent carboxylase activity in lung type II cells but not in lung macrophages.
    Biochem J. 1988 Mar 1;250(2):557-63 PMID: 3355538
  26. A colorimetric procedure for the determination of gamma-carboxyglutamic acid.
    Anal Biochem. 1981 Nov 15;118(1):70-5 PMID: 7337219
  27. Protein S, a new vitamin K-dependent protein from bovine plasma.
    FEBS Lett. 1979 May 15;101(2):377-81 PMID: 109318
  28. Human ingestion of a 'superwarfarin' rodenticide resulting in a prolonged anticoagulant effect.
    JAMA. 1984 Dec 7;252(21):3004-5 PMID: 6502864
  29. Thioredoxin.
    Annu Rev Biochem. 1985;54:237-71 PMID: 3896121
  30. Tissue distribution and warfarin sensitivity of vitamin K epoxide reductase.
    Biochem Pharmacol. 1988 Mar 1;37(5):929-34 PMID: 3345202
  31. Vitamin K-dependent carboxylase. Stoichiometry of carboxylation and vitamin K 2,3-epoxide formation.
    J Biol Chem. 1981 Nov 10;256(21):11032-5 PMID: 7287748
  32. In vitro prothrombin synthesis from a purified precursor protein. III. Preparation of an acid-soluble substrate for vitamin K-dependent carboxylase by limited proteolysis of bovine descarboxyprothrombin.
    Biochim Biophys Acta. 1981 Aug 5;676(1):101-7 PMID: 7020768
  33. Extraction of osteocalcin from fossil bones and teeth.
    Biochem Biophys Res Commun. 1987 Dec 16;149(2):712-9 PMID: 3501291
  34. Mechanism of coumarin action: sensitivity of vitamin K metabolizing enzymes of normal and warfarin-resistant rat liver.
    Biochemistry. 1982 May 11;21(10):2406-11 PMID: 6807339
  35. Blood coagulation factor X mRNA encodes a single polypeptide chain containing a prepro leader sequence.
    Nucleic Acids Res. 1984 Jun 11;12(11):4481-92 PMID: 6330671
  36. Lung, heart, and kidney express high levels of mRNA for the vitamin K-dependent matrix Gla protein. Implications for the possible functions of matrix Gla protein and for the tissue distribution of the gamma-carboxylase.
    J Biol Chem. 1988 Aug 15;263(23):11033-6 PMID: 3042764
  37. Prothrombin activation by an activator from the venom of Oxyuranus scutellatus (Taipan snake).
    J Biol Chem. 1986 Oct 5;261(28):13258-67 PMID: 3531198
  38. The molecular basis of blood coagulation.
    Cell. 1988 May 20;53(4):505-18 PMID: 3286010
  39. Plasma vitamin K1 in mothers and their newborn babies.
    Lancet. 1982 Aug 28;2(8296):460-3 PMID: 6125638
  40. Vitamin K-dependent carboxylase. Solubilization and properties.
    J Biol Chem. 1976 Oct 25;251(20):6238-43 PMID: 977568
  41. Partial purification of bovine liver vitamin K-dependent carboxylase by immunospecific adsorption onto antifactor X.
    FEBS Lett. 1981 Jan 26;123(2):215-8 PMID: 7014242
  42. Characterisation of two differently processed forms of human recombinant factor IX synthesised in CHO cells transformed with a polycistronic vector.
    Eur J Biochem. 1988 Mar 15;172(3):565-72 PMID: 3280312
  43. Tissue distrubution and subcellular localization of bovine thioredoxin determined by radioimmunoassay.
    Biochemistry. 1978 Sep 19;17(19):4071-7 PMID: 101237
  44. A mass-spectrometric method for the estimation of the ratio of gamma-carboxyglutamic acid to glutamic acid at specific sites in proteins. Application to the N-terminal region of bovine prothrombin.
    Biochem J. 1980 Apr 1;187(1):239-43 PMID: 7406863
  45. Rapid assay for gamma-carboxyglutamic acid in urine and bone by precolumn derivatization and reversed-phase liquid chromatography.
    Anal Biochem. 1984 Aug 1;140(2):343-8 PMID: 6486421
  46. Primary structure of bovine matrix Gla protein, a new vitamin K-dependent bone protein.
    J Biol Chem. 1985 Dec 5;260(28):14971-5 PMID: 3877721
  47. Vitamin K 2,3-epoxide reductase: the basis for stereoselectivity of 4-hydroxycoumarin anticoagulant activity.
    Br J Pharmacol. 1988 Nov;95(3):675-82 PMID: 3207986
  48. Purification and properties of a prothrombin activator from the venom of Notechis scutatus scutatus.
    J Biol Chem. 1985 Aug 5;260(16):9366-72 PMID: 3894355
  49. Determination of gamma-carboxyglutamic acid in human urine by gas-liquid chromatography.
    Anal Biochem. 1981 Jul 1;114(2):371-6 PMID: 7304927
  50. Circulating osteocalcin during oral anticoagulant therapy.
    Thromb Haemost. 1988 Aug 30;60(1):79-82 PMID: 3263712
  51. Analysis of gamma-carboxyglutamic acid by reverse phase HPLC of its phenylthiocarbamyl derivative.
    Anal Biochem. 1988 Jul;172(1):241-7 PMID: 3263814
  52. Bovine factor VII. Its purification and complete amino acid sequence.
    J Biol Chem. 1988 Oct 15;263(29):14868-77 PMID: 3049594
  53. Vitamin K-dependent carboxylation. Study of the hydrogen abstraction stereochemistry with gamma-fluoroglutamic acid-containing peptides.
    J Biol Chem. 1983 Jul 10;258(13):7897-9 PMID: 6863270
  54. Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone.
    Biochem Biophys Res Commun. 1983 Dec 28;117(3):765-71 PMID: 6607731
  55. Vitamin K-dependent carboxylase: affinity purification from bovine liver by using a synthetic propeptide containing the gamma-carboxylation recognition site.
    Proc Natl Acad Sci U S A. 1989 Sep;86(18):6893-7 PMID: 2780546
  56. Serum bone gamma carboxyglutamic acid-containing protein in primary hyperparathyroidism and in malignant hypercalcemia. Comparison with bone histomorphometry.
    J Clin Invest. 1986 Mar;77(3):985-91 PMID: 3485113
  57. Primary structure of bovine vitamin K-dependent protein S.
    Proc Natl Acad Sci U S A. 1986 Jun;83(12):4199-203 PMID: 2940598
  58. Protein S and the regulation of activated protein C.
    Semin Thromb Hemost. 1984 Apr;10(2):131-8 PMID: 6234659
  59. The function and metabolism of vitamin K.
    Annu Rev Nutr. 1984;4:281-337 PMID: 6380538
  60. The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors.
    Proc Natl Acad Sci U S A. 1985 Sep;82(18):6109-13 PMID: 3875856
  61. Excessive mineralization with growth plate closure in rats on chronic warfarin treatment.
    Proc Natl Acad Sci U S A. 1982 Dec;79(24):7734-8 PMID: 6984192
  62. Expression of completely gamma-carboxylated recombinant human prothrombin.
    J Biol Chem. 1987 May 15;262(14):6729-34 PMID: 3032975
  63. Vitamin K counteracts the effect of warfarin in liver but not in bone.
    Thromb Res. 1987 Apr 1;46(1):121-31 PMID: 3495903
  64. Vitamin K dependence of a calcium-binding protein containing gamma-carboxyglutamic acid in chicken bone.
    J Biol Chem. 1978 Dec 25;253(24):9063-8 PMID: 721829
  65. Evidence for several gamma-carboxyglutamic acid-containing proteins in dentin.
    Biochim Biophys Acta. 1982 Jun 4;704(2):235-9 PMID: 7104368
  66. Characterization of a gamma-carboxyglutamic acid-containing protein from bone.
    Proc Natl Acad Sci U S A. 1976 May;73(5):1447-51 PMID: 1064018
  67. The placental transport of [3H]vitamin K1 in rats.
    Br J Haematol. 1987 Mar;65(3):335-8 PMID: 3494470
  68. The presence of protein-bound gamma-carboxyglutamic acid in calcium-containing renal calculi.
    J Clin Invest. 1977 Jun;59(6):1151-7 PMID: 864007
  69. Role of vitamin-K-dependent proteins in bone metabolism.
    Annu Rev Nutr. 1988;8:565-83 PMID: 3060178
  70. Vitamin K epoxidase: properties and relationship to prothrombin synthesis.
    Biochemistry. 1977 Aug 23;16(17):3856-63 PMID: 901759
  71. Vitamin K is no antagonist for the action of warfarin in rat osteosarcoma UMR 106.
    Thromb Res. 1988 Apr 1;50(1):27-32 PMID: 3165226
  72. Primary structure of the vitamin K-dependent part of prothrombin.
    FEBS Lett. 1974 Aug 25;44(2):189-93 PMID: 4472513
  73. Expression of active human clotting factor IX from recombinant DNA clones in mammalian cells.
    Nature. 1985 Jun 20-26;315(6021):683-5 PMID: 2989700
  74. Characterization of an almost full-length cDNA coding for human blood coagulation factor X.
    Proc Natl Acad Sci U S A. 1985 Jun;82(11):3591-5 PMID: 2582420
  75. gamma-Carboxyglutamic acid in invertebrates: its identification in hermatypic corals.
    Biochem Biophys Res Commun. 1982 Sep 30;108(2):610-3 PMID: 6128978
  76. Novel 4-hydroxycoumarin anticoagulants active against resistant rats.
    Nature. 1975 Jan 24;253(5489):275-7 PMID: 1113846
  77. Isolation and characterization of a cDNA coding for human factor IX.
    Proc Natl Acad Sci U S A. 1982 Nov;79(21):6461-4 PMID: 6959130
  78. Discovery of a gamma-carboxyglutamic acid-containing protein in human spermatozoa.
    FEBS Lett. 1985 Oct 7;190(1):137-41 PMID: 4043391
  79. Vitamin K dependent modifications of glutamic acid residues in prothrombin.
    Proc Natl Acad Sci U S A. 1974 Jul;71(7):2730-3 PMID: 4528109
  80. Defective propeptide processing of blood clotting factor IX caused by mutation of arginine to glutamine at position -4.
    Cell. 1986 May 9;45(3):343-8 PMID: 3009023
  81. Congenital malformations associated with the administration of oral anticoagulants during pregnancy.
    J Pediatr. 1975 Mar;86(3):459-62 PMID: 1113236
  82. Vitamin K-dependent carboxylase. Possible role for thioredoxin in the reduction of vitamin K metabolites in liver.
    FEBS Lett. 1987 Oct 5;222(2):353-7 PMID: 3308517
  83. New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease.
    J Clin Invest. 1980 Nov;66(5):878-83 PMID: 6968755
  84. Primary structure of the gamma-carboxyglutamic acid-containing protein from bovine bone.
    Proc Natl Acad Sci U S A. 1976 Oct;73(10):3374-5 PMID: 1068450
  85. Cloning and sequencing of liver cDNA coding for bovine protein C.
    Proc Natl Acad Sci U S A. 1984 Sep;81(18):5653-6 PMID: 6091100
  86. Vitamin K-dependent carboxylation. Evidence that at least two microsomal dehydrogenases reduce vitamin K1 to support carboxylation.
    J Biol Chem. 1982 Feb 25;257(4):1583-6 PMID: 6799508
  87. Vitamin K-dependent carboxylase.
    Haematologia (Budap). 1985;18(2):71-97 PMID: 3896983
  88. The content of phylloquinone (vitamin K1) in human milk, cows' milk and infant formula foods determined by high-performance liquid chromatography.
    J Nutr. 1982 Jun;112(6):1105-17 PMID: 7086539
  89. Vitamin K-dependent gamma-carboxyglutamic acid formation by kidney microsomes in vitro.
    Biochem Biophys Res Commun. 1976 Aug 23;71(4):1207-13 PMID: 61755
  90. Propeptide of human protein C is necessary for gamma-carboxylation.
    Biochemistry. 1987 Nov 3;26(22):7003-11 PMID: 3427056
  91. Protein disulphide-isomerase and the formation of native disulphide bonds.
    Biochem Soc Trans. 1984 Dec;12(6):929-32 PMID: 6530042
  92. Production of menaquinones by intestinal anaerobes.
    J Infect Dis. 1984 Aug;150(2):213-8 PMID: 6470528
  93. Vitamin K-dependent carboxylase: increased efficiency of the carboxylation reaction.
    Thromb Haemost. 1987 Feb 3;57(1):77-81 PMID: 3495900
  94. Direct measurement of vitamin K-dependent enzymes in various isolated and cultured tumor and non-tumor cells.
    Mol Cell Biochem. 1987 May;75(1):71-6 PMID: 3627106
  95. The inhibition of vitamin K-dependent carboxylase by cyanide.
    FEBS Lett. 1982 Jan 25;137(2):253-6 PMID: 6277693
  96. Vitamin K-dependent carboxylase. Development of a peptide substrate.
    J Biol Chem. 1976 Sep 25;251(18):5827-30 PMID: 965394
  97. A new detergent for the solubilization of the vitamin K-dependent carboxylation system from liver microsomes: comparison with triton X-100.
    Anal Biochem. 1982 Apr;121(2):315-20 PMID: 7103063
  98. Gamma-carboxyglutamate in a neuroactive toxin.
    J Biol Chem. 1984 Dec 10;259(23):14343-6 PMID: 6501296
  99. Inhibition of hydroxyapatite crystal growth by bone-specific and other calcium-binding proteins.
    Biochemistry. 1986 Mar 11;25(5):1176-80 PMID: 3008822
  100. The latency of rat liver microsomal protein disulphide-isomerase.
    Biochem J. 1985 Jun 15;228(3):635-45 PMID: 3896234
  101. Immunochemical detection and characterisation of osteocalcin from moa bone.
    Biochem Biophys Res Commun. 1985 Jun 28;129(3):714-20 PMID: 3874623
  102. Purification and characterization of the principal inhibitor of calcium oxalate monohydrate crystal growth in human urine.
    J Biol Chem. 1983 Oct 25;258(20):12594-600 PMID: 6630201
  103. Carboxylated calcium-binding proteins and vitamin K.
    N Engl J Med. 1980 Jun 26;302(26):1460-6 PMID: 6990261
  104. The antihaemorrhagic vitamin of the chick.
    Biochem J. 1935 Jun;29(6):1273-85 PMID: 16745789
  105. Vitamin K-dependent carboxylase in skin.
    J Invest Dermatol. 1986 Sep;87(3):377-80 PMID: 3488354
  106. Vitamin K-dependent carboxylase. Demonstration of a vitamin K- and O2-dependent exchange of 3H from 3H2O into glutamic acid residues.
    J Biol Chem. 1983 Oct 25;258(20):12129-31 PMID: 6138349
  107. Vitamin K-dependent carboxylase. Control of enzyme activity by the "propeptide" region of factor X.
    J Biol Chem. 1987 Nov 15;262(32):15334-7 PMID: 2890628
  108. Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins.
    Proc Natl Acad Sci U S A. 1979 Oct;76(10):4990-4 PMID: 291916
  109. Quantitative analysis and comparative decarboxylation of aminomalonic acid, beta-carboxyaspartic acid, and gamma-carboxyglutamic acid.
    Anal Biochem. 1980 Oct;108(1):57-63 PMID: 7457858
  110. A high-performance liquid chromatographic method for the simultaneous determination of gamma-carboxyglutamic acid and glutamic acid in proteins, bone, and urine.
    Anal Biochem. 1981 Nov 1;117(2):259-65 PMID: 6119927
  111. A new carboxylation reaction. The vitamin K-dependent incorporation of H-14-CO3- into prothrombin.
    J Biol Chem. 1975 Jun 25;250(12):4744-8 PMID: 1141226
  112. [3H]diborane reduction of vitamin K-dependent calcium-binding proteins. Identification of a unique amino acid.
    J Biol Chem. 1975 Apr 25;250(8):2968-72 PMID: 1123332
  113. Vitamin K-dependent carboxylases from non-hepatic tissues.
    FEBS Lett. 1982 Nov 8;148(2):317-20 PMID: 7152026
  114. Evidence that warfarin anticoagulant action involves two distinct reductase activities.
    J Biol Chem. 1982 Oct 10;257(19):11210-2 PMID: 6811577
  115. Expression, purification, and characterization of recombinant gamma-carboxylated factor IX synthesized in Chinese hamster ovary cells.
    J Biol Chem. 1986 Jul 25;261(21):9622-8 PMID: 3733688
  116. Characterization of a cDNA coding for human factor VII.
    Proc Natl Acad Sci U S A. 1986 Apr;83(8):2412-6 PMID: 3486420
  117. Calcium-dependent alpha-helical structure in osteocalcin.
    Biochemistry. 1982 May 11;21(10):2538-47 PMID: 6807342
  118. The submicrosomal site for the conversion of prothrombin precursor to biologically active prothrombin in rat liver.
    Biochim Biophys Acta. 1977 Sep 29;499(2):181-93 PMID: 907786
  119. Identification of phospholipid as an essential part of bovine vitamin K-dependent carboxylase.
    J Biol Chem. 1981 Nov 10;256(21):10843-6 PMID: 7287738
  120. Effect of vitamin K administration on acarboxy prothrombin (PIVKA-II) levels in newborns.
    Lancet. 1985 Aug 3;2(8449):242-4 PMID: 2862419
  121. Synthesis of peptide analogues of prothrombin precursor sequence 5-9. Substrate specificity of vitamin K dependent carboxylase.
    J Med Chem. 1981 Jun;24(6):706-11 PMID: 7252980
  122. Circulating vitamin K1 levels in fractured neck of femur.
    Lancet. 1984 Aug 4;2(8397):283 PMID: 6146829
  123. Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition site.
    Proc Natl Acad Sci U S A. 1987 Feb;84(3):634-7 PMID: 3543932
  124. Decarboxylated bone Gla-protein as a substrate for hepatic vitamin K-dependent carboxylase.
    FEBS Lett. 1984 Jan 2;165(1):16-20 PMID: 6607177
  125. Characterization of the complementary deoxyribonucleic acid and gene coding for human prothrombin.
    Biochemistry. 1983 Apr 26;22(9):2087-97 PMID: 6305407
  126. Studies on the absorption and metabolism of phylloquinone (vitamin K1) in man.
    Vitam Horm. 1974;32:513-42 PMID: 4617407
  127. An improved method for the determination of gamma-carboxyglutamic acid in proteins, bone, and urine.
    Anal Biochem. 1983 May;131(1):173-9 PMID: 6614448
  128. Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor.
    Proc Natl Acad Sci U S A. 1986 Aug;83(16):5803-7 PMID: 3461460
  129. Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.
    EMBO J. 1986 Aug;5(8):1885-90 PMID: 3019668
  130. Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase.
    Proc Natl Acad Sci U S A. 1987 Dec;84(23):8335-9 PMID: 3317405
  131. Characterization of bovine prothrombin mRNA and its translation product.
    Biochemistry. 1984 Apr 10;23(8):1626-34 PMID: 6326805
  132. R- and S-Warfarin inhibition of vitamin K and vitamin K 2,3-epoxide reductase activities in the rat.
    J Biol Chem. 1982 May 10;257(9):4894-901 PMID: 7068669
  133. Amino-acid sequence of the vitamin-K-dependent part of protein Z.
    Eur J Biochem. 1982 Aug;126(2):343-8 PMID: 7128593
  134. The effect of vitamin K supplementation on circulating osteocalcin (bone Gla protein) and urinary calcium excretion.
    Ann Intern Med. 1989 Dec 15;111(12):1001-5 PMID: 2556952
  135. The nucleotide sequence of the gene for human protein C.
    Proc Natl Acad Sci U S A. 1985 Jul;82(14):4673-7 PMID: 2991887
  136. Impaired carboxylation of osteocalcin in warfarin-treated patients.
    J Clin Endocrinol Metab. 1987 Jan;64(1):59-61 PMID: 2878010
  137. A case of 'superwarfarin' poisoning.
    Scand J Haematol. 1986 Mar;36(3):314-5 PMID: 3704556
  138. Urinary gamma-carboxyglutamic acid and serum osteocalcin as bone markers: studies in osteoporosis and Paget's disease.
    J Clin Endocrinol Metab. 1983 Dec;57(6):1221-5 PMID: 6605357
  139. Expression of active human factor IX in transfected cells.
    Nature. 1985 Jul 18-24;316(6025):271-3 PMID: 3894976
  140. Vitamin K-dependent gamma-carbon-hydrogen bond cleavage and nonmandatory concurrent carboxylation of peptide-bound glutamic acid residues.
    Proc Natl Acad Sci U S A. 1979 Jul;76(7):3126-9 PMID: 290992
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj2660625
Published
1990-03-15
Pages
625-36
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1131186
Subset
IM
External Links
PubMed source DOI: 10.1042/bj2660625 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2