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PMID: 24639412 Published · ppublish English Journal Article Review

Epidemiology of bronchopulmonary dysplasia.

Birth defects research. Part A, Clinical and molecular teratology ·Vol. 100 ·No. 3 ·2014-03-00 ·Pages 145-57

Jensen EA, Schmidt B

Abstract

Bronchopulmonary dysplasia (BPD) is among the most common and serious sequelae of preterm birth. BPD affects at least one-quarter of infants born with birth weights less than 1500 g. The incidence of BPD increases with decreasing gestational age and birth weight. Additional important risk factors include intrauterine growth restriction, sepsis, and prolonged exposure to mechanical ventilation and supplemental oxygen. The diagnosis of BPD predicts multiple adverse outcomes including chronic respiratory impairment and neurodevelopmental delay. This review summarizes the diagnostic criteria, incidence, risk factors, and long-term outcomes of BPD.

Keywords
bronchopulmonary dysplasia chronic lung disease epidemiology mechanical ventilation very low birth weight
MeSH Terms
Bronchopulmonary Dysplasia/diagnosis,epidemiology,etiology,therapy Female Humans Incidence Infant, Low Birth Weight Infant, Newborn Infant, Premature Male Risk Factors
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Jensen Erik A
Division of Neonatology, The Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania.
Schmidt Barbara
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Article Info
Journal
Birth defects research. Part A, Clinical and molecular teratology
Abbr.
Birth Defects Res A Clin Mol Teratol
ISSN
1542-0760
DOI
10.1002/bdra.23235
Published
2014-03-00
Epub
2014-00-17
Pages
145-57
Language
English
Region
United States
NLM ID
101155107
PMCID
PMC8604158
Subset
IM
Grants
NICHD NIH HHS · T32 HD060550 · United States
External Links
PubMed source DOI: 10.1002/bdra.23235 PMC Full Text
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