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PMID: 2499683 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Codon reassignment (codon capture) in evolution.

Journal of molecular evolution ·Vol. 28 ·No. 4 ·1989-04-00 ·Pages 271-8

Osawa S, Jukes TH

Abstract

The genetic code, once thought to be "frozen," shows variations from the universal code. Variations are found in mitochondria, Mycoplasma, and ciliated protozoa. The variations result from reassignment of codons, especially stop codons. The reassignments take place by disappearance of a codon from coding sequences, followed by its reappearance in a new role. Simultaneously, a changed anticodon must appear. We discuss the role of directional mutation pressure in the events, and we also describe the possibility that such events have taken place during early evolution of the genetic code and can occur during its present evolution.

MeSH Terms
Animals Biological Evolution Codon/genetics DNA, Mitochondrial/genetics Eukaryota/genetics Genetic Code Mutation Mycoplasma/genetics RNA, Messenger/genetics
Chemicals
Codon DNA, Mitochondrial RNA, Messenger
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Osawa S
Nagoya University, Department of Biology, Japan.
Jukes T H
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48 references, click to expand
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Article Info
Journal
Journal of molecular evolution
Abbr.
J Mol Evol
ISSN
0022-2844
DOI
10.1007/BF02103422
Published
1989-04-00
Pages
271-8
Language
English
Region
Germany
NLM ID
0360051
Subset
IM
External Links
PubMed source DOI: 10.1007/BF02103422 View journal details
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