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PMID: 2675759 Published · ppublish English Journal Article Review

Methicillin-resistant staphylococci: genetics and mechanisms of resistance.

Antimicrobial agents and chemotherapy ·Vol. 33 ·No. 7 ·1989-07-00 ·Pages 991-4

Hackbarth CJ, Chambers HF

Abstract

暂无摘要

MeSH Terms
Methicillin/pharmacology Penicillin Resistance Staphylococcus/drug effects,genetics
Chemicals
Methicillin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hackbarth C J
Medical Service, San Francisco General Hospital, California.
Chambers H F
References (49)
49 references, click to expand
  1. IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgaris.
    Gene. 1987;59(1):107-13 PMID: 2830163
  2. Properties of the penicillin-binding proteins of Escherichia coli K12,.
    Eur J Biochem. 1977 Jan;72(2):341-52 PMID: 319999
  3. Penicillin-binding proteins in a Staphylococcus aureus strain resistant to specific beta-lactam antibiotics.
    Antimicrob Agents Chemother. 1982 Jul;22(1):172-5 PMID: 7125630
  4. Conversion of a homogeneously methicillin-resistant strain of Staphylococcus aureus to heterogeneous resistance by Tn551-mediated insertional inactivation.
    Eur J Clin Microbiol. 1986 Dec;5(6):714-8 PMID: 3026802
  5. Genetics of staphylococcal enterotoxin B in methicillin-resistant isolates of Staphylococcus aureus.
    Infect Immun. 1979 Sep;25(3):902-11 PMID: 259057
  6. Transduction of Methicillin Resistance in Staphylococcus aureus Dependent on an Unusual Specificity of the Recipient Strain.
    J Bacteriol. 1970 Dec;104(3):1158-67 PMID: 16559089
  7. Genetic and molecular characterisation of resistance determinants in methicillin-resistant Staphylococcus-aureus.
    J Med Microbiol. 1976 May;9(2):137-48 PMID: 1047111
  8. Production of low-affinity penicillin-binding protein by low- and high-resistance groups of methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 1987 Sep;31(9):1307-11 PMID: 3499861
  9. Extrachromosomal control of methicillin resistance and toxin production in Staphylococcus aureus.
    J Bacteriol. 1969 May;98(2):351-8 PMID: 5192681
  10. Synthesis of peptidoglycan in vivo in methicillin-resistant Staphylococcus aureus.
    Eur J Biochem. 1982 Oct;127(3):553-8 PMID: 7173195
  11. Recipient characteristics in the transduction of methicillin resistance in Staphylococcus epidermidis.
    Antimicrob Agents Chemother. 1986 Mar;29(3):539-41 PMID: 2940975
  12. Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus.
    Antimicrob Agents Chemother. 1986 Jan;29(1):85-92 PMID: 3488015
  13. Increased amounts of a novel penicillin-binding protein in a strain of methicillin-resistant Staphylococcus aureus exposed to nafcillin.
    J Clin Invest. 1985 Jul;76(1):325-31 PMID: 4019783
  14. Genetic behavior of the methicillin resistance determinant in Staphylococcus aureus.
    J Bacteriol. 1980 Dec;144(3):1200-2 PMID: 6254946
  15. Spontaneous loss of methicillin resistance in Staphylococcus aureus at room-temperature.
    Lancet. 1972 Dec 9;2(7789):1257 PMID: 4117751
  16. Cloning and expression of methicillin resistance from Staphylococcus epidermidis in Staphylococcus carnosus.
    Antimicrob Agents Chemother. 1988 Oct;32(10):1494-9 PMID: 2903715
  17. Suppression of intrinsic resistance to penicillins in Staphylococcus aureus by polidocanol, a dodecyl polyethyleneoxid ether.
    Antimicrob Agents Chemother. 1985 Apr;27(4):632-9 PMID: 3873904
  18. Binding of beta-lactam antibiotics to penicillin-binding proteins of Staphylococcus aureus and Streptococcus faecalis: relation to antibacterial activity.
    Antimicrob Agents Chemother. 1980 Nov;18(5):834-6 PMID: 6778388
  19. Identification of a Staphylococcus aureus transposon (Tn4291) that carries the methicillin resistance gene(s).
    J Bacteriol. 1988 Jan;170(1):149-54 PMID: 2826391
  20. Unique features in the ribosome binding site sequence of the gram-positive Staphylococcus aureus beta-lactamase gene.
    J Biol Chem. 1981 Nov 10;256(21):11283-91 PMID: 6793593
  21. Regulation of penicillin-binding protein activity: description of a methicillin-inducible penicillin-binding protein in Staphylococcus aureus.
    Antimicrob Agents Chemother. 1985 May;27(5):828-31 PMID: 3848293
  22. Occurrence of a beta-lactam-inducible penicillin-binding protein in methicillin-resistant staphylococci.
    Antimicrob Agents Chemother. 1985 May;27(5):851-7 PMID: 3848294
  23. Transduction of methicillin resistance in Staphylococcus aureus: recipient effectiveness and beta-lactamase production.
    Antimicrob Agents Chemother. 1980 Sep;18(3):424-32 PMID: 6448580
  24. Molecular cloning of the gene of a penicillin-binding protein supposed to cause high resistance to beta-lactam antibiotics in Staphylococcus aureus.
    J Bacteriol. 1986 Sep;167(3):975-80 PMID: 3638304
  25. Transformation reveals a chromosomal locus of the gene(s) for methicillin resistance in Staphylococcus aureus.
    J Bacteriol. 1975 Sep;123(3):905-15 PMID: 125746
  26. Transduction of penicillinase production and methicillin resistance-enterotoxin B production in strains of Staphylococcus aureus.
    J Gen Microbiol. 1973 May;76(1):1-11 PMID: 4489832
  27. Detection of an integrated tetracycline resistance plasmid in the chromosome of methicillin-resistant Staphylococcus aureus.
    J Gen Microbiol. 1986 Jun;132(6):1723-8 PMID: 3643251
  28. Role of an altered penicillin-binding protein in methicillin- and cephem-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 1985 Sep;28(3):397-403 PMID: 3878127
  29. The expression in Staphylococcus aureus of cloned DNA encoding methicillin resistance.
    J Gen Microbiol. 1988 Jun;134(6):1465-9 PMID: 3221195
  30. Penicillin-binding proteins and the mechanism of action of beta-lactam antibiotics.
    Annu Rev Biochem. 1983;52:825-69 PMID: 6351730
  31. Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus.
    J Bacteriol. 1984 May;158(2):513-6 PMID: 6563036
  32. DOMINANCE OF THE INDUCIBLE STATE IN STRAINS OF STAPHYLOCOCCUS AUREUS CONTAINING TWO DISTINCT PENICILLINASE PLASMIDS.
    J Bacteriol. 1965 Aug;90:370-4 PMID: 14329449
  33. Possible physiological functions of penicillin-binding proteins in Staphylococcus aureus.
    Antimicrob Agents Chemother. 1986 Feb;29(2):333-6 PMID: 3521479
  34. Transduction of staphylococcal enterotoxin B synthesis: establishment of the toxin gene in a recombination-deficient mutant.
    Infect Immun. 1980 Jan;27(1):280-2 PMID: 7358431
  35. Additional DNA in methicillin-resistant Staphylococcus aureus and molecular cloning of mec-specific DNA.
    J Bacteriol. 1986 Feb;165(2):373-8 PMID: 3003024
  36. Nucleotide sequence of the penicillinase repressor gene penI of Bacillus licheniformis and regulation of penP and penI by the repressor.
    J Bacteriol. 1986 Dec;168(3):1128-32 PMID: 3096969
  37. Absence of circular plasmid deoxyribonucleic acid attributable to a genetic determinant for methicillin resistance in Staphylococcus aureus.
    J Bacteriol. 1973 Nov;116(2):771-7 PMID: 4490525
  38. Chromosomal map location of the methicillin resistance determinant in Staphylococcus aureus.
    J Bacteriol. 1978 Aug;135(2):460-5 PMID: 249312
  39. Mercury and tetracycline resistance genes and flanking repeats associated with methicillin resistance on the chromosome of Staphylococcus aureus.
    Mol Microbiol. 1988 Mar;2(2):289-92 PMID: 2837617
  40. Penicillin-binding proteins of beta-lactam-resistant strains of Staphylococcus aureus. Effect of growth conditions.
    FEBS Lett. 1985 Nov 11;192(1):28-32 PMID: 3850810
  41. Coagulase-negative staphylococci resistant to beta-lactam antibiotics in vivo produce penicillin-binding protein 2a.
    Antimicrob Agents Chemother. 1987 Dec;31(12):1919-24 PMID: 3439802
  42. Effect of NaCl and nafcillin on penicillin-binding protein 2a and heterogeneous expression of methicillin resistance in Staphylococcus aureus.
    Antimicrob Agents Chemother. 1987 Dec;31(12):1982-8 PMID: 3439805
  43. Intrinsic resistance to beta-lactam antibiotics in Staphylococcus aureus.
    FEBS Lett. 1980 Dec 29;122(2):275-8 PMID: 7202719
  44. Transduction and elimination of resistance determinants in methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 1972 Sep;2(3):217-23 PMID: 4494517
  45. Effects of growth of methicillin-resistant and -susceptible Staphylococcus aureus in the presence of beta-lactams on peptidoglycan structure and susceptibility to lytic enzymes.
    Antimicrob Agents Chemother. 1986 Feb;29(2):250-7 PMID: 2872855
  46. The cloning of chromosomal DNA associated with methicillin and other resistances in Staphylococcus aureus.
    J Gen Microbiol. 1987 Jul;133(7):1919-29 PMID: 3668502
  47. Evolution of an inducible penicillin-target protein in methicillin-resistant Staphylococcus aureus by gene fusion.
    FEBS Lett. 1987 Aug 31;221(1):167-71 PMID: 3305073
  48. Antimicrobial resistance of Staphylococcus aureus: genetic basis.
    Microbiol Rev. 1987 Mar;51(1):88-134 PMID: 3031442
  49. Genetic control in methicillin-resistant strains of Staphylococcus aureus.
    J Med Microbiol. 1972 Nov;5(4):497-508 PMID: 4486061
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.33.7.991
Published
1989-07-00
Pages
991-4
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC176050
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.33.7.991 PMC Full Text View journal details
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