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PMID: 3070354 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The F factor of Escherichia coli carries a locus of stable plasmid inheritance stm, similar to the parB locus of plasmid RI.

Molecular & general genetics : MGG ·Vol. 214 ·No. 2 ·1988-10-00 ·Pages 353-7

Golub EI, Panzer HA

Abstract

We found that a 1.4 kb fragment of the F factor of Escherichia coli (coordinates 62.8-64.2) considerably increased the stable inheritance of different plasmids which carried it. The fragment has a 589 bp DNA sequence (coordinates 63.3-63.9) with extensive homology to the parB locus of plasmid RI and, probably like the parB region, ensures the presence of plasmids in bacterial populations by killing those cells which have lost the plasmid.

MeSH Terms
Base Sequence Cloning, Molecular DNA, Bacterial/genetics Escherichia coli/genetics F Factor Molecular Sequence Data Nucleic Acid Hybridization R Factors Restriction Mapping
Chemicals
DNA, Bacterial
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Golub E I
Radiobiology Laboratories, Yale University School of Medicine, New Haven, CT 06510.
Panzer H A
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25 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00337735
Published
1988-10-00
Pages
353-7
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
Grants
NCI NIH HHS · CA39238 · United States
External Links
PubMed source DOI: 10.1007/BF00337735
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