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Metabolites of arachidonic acid formed by human gastrointestinal tissues and their actions on the muscle layers.
Br J Pharmacol. 1981 Oct;74(2):435-44
PMID: 7317691
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Sulfasalazine inhibits the synthesis of chemotactic lipids by neutrophils.
J Clin Invest. 1982 Feb;69(2):494-7
PMID: 6120182
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Laxative-like effects of nonsteroidal anti-inflammatory drugs on intestinal fluid movement and membrane integrity.
J Pharmacol Exp Ther. 1982 Feb;220(2):236-42
PMID: 6948953
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Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel.
Gastroenterology. 1982 Apr;82(4):673-9
PMID: 6949849
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Recent developments in "nonspecific" inflammatory bowel disease (first of two parts).
N Engl J Med. 1982 Apr 1;306(13):775-85
PMID: 7038488
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Ulcerative colitis: effect of sulphasalazine, its metabolites and indomethacin on the ability of human colonic mucosa to metabolize prostaglandins in vitro.
Br J Pharmacol. 1982 May;76(1):157-61
PMID: 6123357
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The pharmacology of benoxaprofen with particular to effects on lipoxygenase product formation.
Eur J Rheumatol Inflamm. 1982;5(2):61-8
PMID: 6806104
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Evidence that prednisolone is inhibitory to the cyclooxygenase activity of human rectal mucosa.
Prostaglandins. 1982 Mar;23(3):397-409
PMID: 6808592
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Stimulation of colonic secretion by lipoxygenase metabolites of arachidonic acid.
Science. 1982 Sep 24;217(4566):1255-6
PMID: 6810465
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Prostaglandins and the splanchnic circulation.
Proc Soc Exp Biol Med. 1982 Sep;170(4):391-7
PMID: 6750616
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Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate.
J Biol Chem. 1983 Jan 25;258(2):764-9
PMID: 6822511
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Analgesic ingestion and other factors preceding relapse in ulcerative colitis.
Gut. 1983 Mar;24(3):187-9
PMID: 6826100
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Inhibition of prostaglandin synthetase in human rectal mucosa.
Gut. 1983 Mar;24(3):213-7
PMID: 6131017
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Inhibition of soybean lipoxygenase by sulfasalazine and 5-aminosalicylic acid: a possible mode of action in ulcerative colitis.
Biochem Pharmacol. 1983 Jan 1;32(1):170-2
PMID: 6131674
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Increased colonic adenylate cyclase activity in active ulcerative colitis.
Gastroenterology. 1983 Jul;85(1):12-6
PMID: 6303887
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[Prostaglandine in a darmstoff preparation from frog intestine].
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1965 Nov 4;252(1):68-78
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Small intestinal ulcers and intestinal flora in rats given indomethacin.
Am J Pathol. 1969 Feb;54(2):237-49
PMID: 5765565
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Effect of oral prostaglandin E1 on intestinal transit in man.
Lancet. 1969 Mar 29;1(7596):648-51
PMID: 4179885
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Effect of orally administered prostaglandin E1 on gastric secretion and gastrointestinal motility in man.
Gut. 1968 Dec;9(6):655-8
PMID: 5717966
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Therapeutic abortion using prostaglandin F2alpha.
Lancet. 1970 Jan 24;1(7639):157-9
PMID: 4189236
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Absorption and secretion of water and electrolytes by the intact human colon in diffuse untreated proctocolitis.
Gut. 1970 Jan;11(1):27-33
PMID: 5435265
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Prostaglandins and the gastrointestinal tract.
Gastroenterology. 1970 Nov;59(5):790-800
PMID: 4920061
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Stimulation of intestinal mucosal adenyl cyclase by cholera enterotoxin and prostaglandins.
J Clin Invest. 1971 Jun;50(6):1218-30
PMID: 4325309
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The effect of salazopyrin on water and electrolyte transport in the human colon measured in vivo and in vitro.
Gut. 1972 Oct;13(10):855
PMID: 4404481
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The absorption and secretion of water and electrolytes across the healthy and the diseased human colonic mucosa measured in vitro.
Gut. 1972 Nov;13(11):880-6
PMID: 4646291
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Protective effect of prostaglandin E 1 (PGE 1 ) on lysosomal enzyme release in serotonin-induced gastric ulceration.
Ann Surg. 1973 Jun;177(6):648-54
PMID: 4708640
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Prostaglandins and the gastrointestinal tract.
Gut. 1973 May;14(5):402-17
PMID: 4577412
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Electrical potential difference and sodium and potassium fluxes across rectal mucosa in ulcerative colitis.
Gut. 1973 Oct;14(10):784-9
PMID: 4758659
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Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. Evidence against an essential role for prostaglandins in the action of toxin.
J Clin Invest. 1974 Mar;53(3):941-9
PMID: 4359941
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Letter: Rectal bleeding and indomethacin suppositories.
Lancet. 1975 Mar 8;1(7906):577
PMID: 47052
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Colonic and small intestinal response to intravenous prostaglandin F2 alpha and E2 in man.
Gut. 1975 Jan;16(1):42-6
PMID: 1140624
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The effect of intravenous prostaglandin F2 alpha and E2 on the motility of the sigmoid colon.
Gut. 1975 Jan;16(1):47-9
PMID: 1140625
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Letter: Prostaglandins, ulcerative colitis, and sulphasalazine.
Lancet. 1975 Nov 15;2(7942):988
PMID: 53480
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Inhibition of prostaglandin biosynthesis by sulphasalazine and its metabolites.
Prostaglandins. 1976 Feb;11(2):219-25
PMID: 4854
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Effect of carbenoxolone on prostaglandin synthesis and degradation.
J Pharm Pharmacol. 1976 Feb;28(2):146-8
PMID: 6674
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Assay of prostaglandin-like substances in faeces and their measurement in ulcerative colitis.
Prostaglandins. 1976 Mar;11(3):489-97
PMID: 948621
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Prostaglandins as mediators of inflammation.
Adv Prostaglandin Thromboxane Res. 1976;2:791-801
PMID: 790919
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Stimulation of colonic glycoprotein synthesis by dibutyryl cyclic AMP and theophylline.
Gastroenterology. 1977 Jan;72(1):82-6
PMID: 186353
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Regional intestinal blood flow in ulcerative colitis and Crohn's disease.
Gastroenterology. 1977 Mar;72(3):388-96
PMID: 832785
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Prostaglandins from tumours of human large bowel.
Br J Cancer. 1977 Jun;35(6):881-4
PMID: 871372
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Increased prostaglandin production in ulcerative colitis.
Lancet. 1977 Jul 9;2(8028):98
PMID: 69189
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An experiment to determine the active therapeutic moiety of sulphasalazine.
Lancet. 1977 Oct 29;2(8044):892-5
PMID: 72239
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Estimation and characterization of prostaglandins in the human gastrointestinal tract.
Br J Pharmacol. 1977 Dec;61(4):579-86
PMID: 597665
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Benoxaprofen in the treatment of active ulcerative colitis.
Prostaglandins Leukot Med. 1983 Apr;10(4):405-9
PMID: 6407032
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Increased oxidation of a chemical carcinogen, benzo(a)pyrene, by colon tissue biopsy specimens from patients with ulcerative colitis.
Gastroenterology. 1983 Aug;85(2):328-34
PMID: 6305757
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Prostanoid synthesis by cultured intestinal epithelial and mononuclear cells in inflammatory bowel disease.
Gut. 1983 Jul;24(7):659-64
PMID: 6345283
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Inhibition of platelet thromboxane synthetase by sulfasalazine.
Biochem Pharmacol. 1983 Jul 15;32(14):2205-9
PMID: 6135423
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Prostanoids cytoprotection for maintaining remission in ulcerative colitis. Failure of 15(R), 15-methylprostaglandin E2.
Dig Dis Sci. 1983 Sep;28(9):807-11
PMID: 6136395
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Influence of long-term 16,16-dimethyl prostaglandin E2 treatment on the rat gastrointestinal mucosa.
Gastroenterology. 1983 Nov;85(5):1003-10
PMID: 6618097
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Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease.
Gut. 1983 Oct;24(10):881-5
PMID: 6578172
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Immunoregulatory activity of metabolites of arachidonic acid and their role in inflammation.
Br Med Bull. 1983 Jul;39(3):243-8
PMID: 6313115
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Enteritis and colitis associated with mefenamic acid.
Br Med J (Clin Res Ed). 1983 Oct 22;287(6400):1182
PMID: 6414618
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Intestinal perforation associated with osmotic slow release indomethacin capsules.
Br Med J (Clin Res Ed). 1983 Dec 3;287(6406):1671-2
PMID: 6416544
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Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa.
Gut. 1983 Dec;24(12):1176-82
PMID: 6416934
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Enhanced synthesis of leukotriene B4 by colonic mucosa in inflammatory bowel disease.
Gastroenterology. 1984 Mar;86(3):453-60
PMID: 6319219
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Are prostaglandins cytoprotective in the human large intestine? The effect of indomethacin on rectal mucosal function and prostaglandin E2 release in vivo.
Agents Actions. 1984 Jun;14(5-6):715-8
PMID: 6591772
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The motility of the pelvic colon. II. Paradoxical motility in diarrhoea and constipation.
Gut. 1962 Dec;3:342-8
PMID: 14022607
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SERUM ELECTROLYTES AND COLONIC TRANSFER OF WATER AND ELECTROLYTES IN CHRONIC ULCERATIVE COLITIS.
Gastroenterology. 1964 Nov;47:525-30
PMID: 14226223
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Release of mediators of anaphylaxis: inhibition of prostaglandin synthesis and the modification of release of slow reacting substance of anaphylaxis and histamine.
Br J Pharmacol. 1978 Jan;62(1):61-6
PMID: 74266
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Is the effect of diphenolic laxatives mediated via release of prostaglandin E?
Experientia. 1978 Mar 15;34(3):386-7
PMID: 631275
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Stimulation of mucus and nonparietal cell secretion by the E2 prostaglandins.
Am J Dig Dis. 1978 Apr;23(4):359-64
PMID: 665632
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Indomethacin and naproxen suppositories in the treatment of rheumatoid arthritis.
Ann Rheum Dis. 1978 Aug;37(4):370-2
PMID: 356764
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The role of prostaglandins in the study of intestinal water and electrolyte transport in man.
Biomedicine. 1978 May-Jun;28(3):143-8
PMID: 212132
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Sulphasalazine is a potent inhibitor of prostaglandin 15-hydroxydehydrogenase: possible basis for therapeutic action in ulcerative colitis.
Br J Pharmacol. 1978 Sep;64(1):6-8
PMID: 29685
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Role of prostaglandins in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine.
Gastroenterology. 1978 Oct;75(4):638-40
PMID: 30669
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The ubiquitous prostaglandins and their role in ulcerative colitis.
Gastroenterology. 1978 Oct;75(4):748-50
PMID: 30671
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Determination of prostaglandin synthetase activity in rectal biopsy material and its significance in colonic disease.
Gut. 1978 Oct;19(10):875-7
PMID: 101423
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Inhibition by propranolol of bile acid- and PGE1-stimulated camp and intestinal secretion.
Am J Gastroenterol. 1978 Aug;70(2):129-35
PMID: 213967
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Venous prostaglandin-like activity in diarrhoeal states.
Gut. 1978 Nov;19(11):1057-8
PMID: 730074
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Gastrointestinal cytoprotection by prostaglandins.
Gut. 1979 Jan;20(1):75-87
PMID: 367886
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Prostaglandins and ulcerative colitis.
Gastroenterology. 1979 May;76(5 Pt 1):1083
PMID: 374175
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Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway.
J Immunol. 1979 Apr;122(4):1563-71
PMID: 109510
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Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation.
Nature. 1979 Mar 29;278(5703):456-9
PMID: 450050
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Cytoprotection by prostaglandins.
Gastroenterology. 1979 Oct;77(4 Pt 1):761-7
PMID: 38173
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A note on indomethacin suppositories in rheumatic conditions.
Rheumatol Rehabil. 1979 Aug;18(3):186-7
PMID: 315090
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On the effect of sulphasalazine on the prostaglandin system and the defective prostaglandin inactivation observed in experimental ulcerative colitis.
Agents Actions Suppl. 1979;(4):232-44
PMID: 40410
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Prostaglandin synthetase activity in acute ulcerative colitis: effects of treatment with sulphasalazine, codeine phosphate and prednisolone.
Gut. 1979 Sep;20(9):802-5
PMID: 40848
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Prostaglandins, indomethacin, and ulcerative colitis.
Gastroenterology. 1980 Jan;78(1):193
PMID: 7350030
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Saturation kinetics applied to in vitro effects of low prostaglandin E2 and F 2 alpha concentrations on ion transport across human jejunal mucosa.
Gastroenterology. 1980 Jan;78(1):32-42
PMID: 6243108
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New modes for regulating intestinal ion transport.
Gastroenterology. 1980 Mar;78(3):642-4
PMID: 6101317
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Human colonic adenylate cyclase. Stimulation of enzyme activity by vasoactive intestinal peptide and various prostaglandins via distinct receptor sites.
Digestion. 1980;20(1):62-7
PMID: 6243592
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Intestinal blood flow.
Gastroenterology. 1980 Apr;78(4):837-63
PMID: 6101568
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PGE2 stimulates gastric chloride transport: possible key to cytoprotection.
Nature. 1980 Feb 14;283(5748):671-3
PMID: 6965522
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The effect of prostacyclin on intestinal ion transport in the rat.
Life Sci. 1980 Jan 14;26(2):123-31
PMID: 6245315
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Effects of prostaglandin E1, administered by gastric intubation, on mucus secretory patterns in rat small intestine.
Adv Prostaglandin Thromboxane Res. 1980;8:1589-93
PMID: 7377005
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Rectal mucosal prostaglandin E release and electrolyte transport in ulcerative colitis.
Adv Prostaglandin Thromboxane Res. 1980;8:1621-5
PMID: 7377010
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Inflammation: the role of peroxidase-derived products.
Adv Prostaglandin Thromboxane Res. 1980;6:77-86
PMID: 6770608
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Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes.
Nature. 1980 Jul 17;286(5770):264-5
PMID: 6250050
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Review: prostaglandins and cancer.
Prostaglandins Med. 1980 Jul;5(1):11-28
PMID: 6250176
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Prostaglandins and prostaglandin metabolites in human gastric juice.
Prostaglandins. 1980 Aug;20(2):419-27
PMID: 6893366
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Effect of somatostatin on ion transport in the rat colon.
J Clin Invest. 1980 Oct;66(4):813-20
PMID: 6106653
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Electrolyte transport across colonic mucosa from patients with inflammatory bowel disease.
Gastroenterology. 1980 Sep;79(3):508-11
PMID: 7429111
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Rectal mucosal prostaglandin E2 release and its relation to disease activity, electrical potential difference, and treatment in ulcerative colitis.
Gut. 1980 Jul;21(7):591-6
PMID: 7429322
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Ulcerative enterocolitis in dogs induced by drugs.
J Pathol. 1980 Aug;131(4):363-78
PMID: 6107336
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Prostaglandins and diarrhea.
Dig Dis Sci. 1980 Dec;25(12):897-9
PMID: 7449585
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Effect of prostaglandin on ion transport across isolated colonic mucosa.
Dig Dis Sci. 1980 Dec;25(12):900-4
PMID: 6256142
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Prostaglandins as mediators of paraneoplastic syndromes: review and up-date.
Metabolism. 1981 Mar;30(3):299-316
PMID: 7010075
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Prostaglandin E2-mediated secretory diarrhea in villous adenoma of rectum: effect of treatment with indomethacin.
Gastroenterology. 1981 Jun;80(6):1562-6
PMID: 7227779
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Effect of prednisolone on prostaglandin synthesis by rectal mucosa in ulcerative colitis: investigation by laminar flow bioassay and radioimmunoassay.
Gut. 1981 Mar;22(3):190-3
PMID: 7227851
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Prostaglandin synthesis inhibitors in ulcerative colitis: flurbiprofen compared with conventional treatment.
Prostaglandins. 1981 Mar;21(3):417-25
PMID: 6112777
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The effect of sulphasalazine withdrawal on rectal mucosal function and prostaglandin E2 release in inactive ulcerative colitis.
Scand J Gastroenterol. 1981;16(1):157-9
PMID: 6112788
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Studies of prostaglandins and sulphasalazine in ulcerative colitis.
Prostaglandins Med. 1981 Feb;6(2):165-82
PMID: 6113614
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Enhanced thromboxane A2 and prostacyclin production by cultured rectal mucosa in ulcerative colitis and its inhibition by steroids and sulfasalazine.
Gastroenterology. 1981 Sep;81(3):444-9
PMID: 6114012
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5-Aminosalicylic acid, a co-factor for colonic prostacyclin synthesis?
Lancet. 1981 Aug 1;2(8240):255
PMID: 6114307
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Polycyclic aromatic hydrocarbon oxidation during prostaglandin biosynthesis.
Life Sci. 1981 Aug 10;29(6):531-46
PMID: 6268915
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Role of prostaglandins in bile salt-induced changes in rat colonic structure and function.
Clin Sci (Lond). 1981 Nov;61(5):641-8
PMID: 7285509
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Relapse of ulcerative proctocolitis during treatment with non-steroidal anti-inflammatory drugs.
Postgrad Med J. 1981 May;57(667):297-9
PMID: 6117846