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PMID: 6272217 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The atp operon: nucleotide sequence of the genes for the gamma, beta, and epsilon subunits of Escherichia coli ATP synthase.

Nucleic acids research ·Vol. 9 ·No. 20 ·1981-10-24 ·Pages 5287-96

Saraste M, Gay NJ, Eberle A, Runswick MJ, Walker JE

Abstract

The nucleotide sequence of the promoter distal region of the atp (or unc) operon of Escherichia coli has been determined. It encodes the gamma, beta and epsilon subunits of the ATP-synthase complex and includes a noncoding sequence in which transcription of the operon probably terminates. This work completes the nucleotide sequence of the operon which contains nine genes: eight encode structural proteins of the ATP-synthase complex; a ninth, the first in the operon, may be a pilot for assembly. The genes for the alpha and beta subunits have evolved from a common ancestor.

MeSH Terms
ATP Synthetase Complexes Adenosine Diphosphate/genetics Adenosine Triphosphatases/genetics Base Sequence Cloning, Molecular DNA, Bacterial/genetics Escherichia coli/enzymology Genes Multienzyme Complexes/genetics Operon Phosphotransferases/genetics Plasmids Proton-Translocating ATPases
Chemicals
DNA, Bacterial Multienzyme Complexes Adenosine Diphosphate Phosphotransferases ATP Synthetase Complexes Adenosine Triphosphatases Proton-Translocating ATPases
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Saraste M
Gay N J
Eberle A
Runswick M J
Walker J E
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20 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/9.20.5287
Published
1981-10-24
Pages
5287-96
Language
English
Region
England
NLM ID
0411011
PMCID
PMC327520
Subset
IM
Databases
GENBANK
V00267
External Links
PubMed source DOI: 10.1093/nar/9.20.5287 PMC Full Text View journal details
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