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PMID: 6818550 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 79 ·No. 24 ·1982-12-00 ·Pages 7809-13

Trent JM, Olson S, Lawn RM

Abstract

Recombinant plasmids containing cDNA inserts from human leukocyte interferon (IFN-alpha), fibroblast interferon (IFN-beta), or immune interferon (INF-gamma) genes were radiolabeled and hybridized in situ to human metaphase chromosome preparations. The results localized the human IFN-alpha and IFN-beta genes to the short arm of chromosome 9(p21-->pter) and localized the IFN-gamma gene to the long arm of chromosome 12(q24.1).

MeSH Terms
Chromosome Banding Chromosome Mapping Chromosomes, Human, 6-12 and X Humans Interferon Type I/genetics Interferon-gamma/genetics Nucleic Acid Hybridization
Chemicals
Interferon Type I Interferon-gamma
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Trent J M
Olson S
Lawn R M
References (35)
35 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.79.24.7809
Published
1982-12-00
Pages
7809-13
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC347438
Subset
IM
Grants
NCI NIH HHS · CA-17094 · United States
NCI NIH HHS · CA-29476 · United States
External Links
PubMed source DOI: 10.1073/pnas.79.24.7809 PMC Full Text View journal details
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