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PMID: 8099441 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 90 ·No. 10 ·1993-05-15 ·Pages 4490-4

Li J, Vogt PK

Abstract

Avian sarcoma virus 31 contains an oncogene that we have named qin. qin codes for a nuclear protein, Qin, that is a member of the HNF-3/fork head family of transcriptional regulators. Within this family Qin is particularly closely related to rat brain factor 1 (BF-1), a telencephalon-specific gene presumed to play an important role in the development of the mammalian brain.

Related Genes
BF1 HNF3&agr HNF3&bgr HNF3&ggr ILF XFKH1 fkh qin slp1 slp2
MeSH Terms
Amino Acid Sequence Animals Avian Sarcoma Viruses/genetics Base Sequence Cell Transformation, Neoplastic/genetics Cell Transformation, Viral Chickens Cloning, Molecular Gene Expression Genes, Homeobox Molecular Sequence Data Multigene Family Nuclear Proteins/genetics Oncogenes RNA, Messenger/genetics Sequence Alignment Transcription Factors/genetics
Chemicals
Nuclear Proteins RNA, Messenger Transcription Factors
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Li J
Department of Microbiology, University of Southern California School of Medicine, Los Angeles 90033-1034.
Vogt P K
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24 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.90.10.4490
Published
1993-05-15
Pages
4490-4
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC46537
Subset
IM
Grants
NCI NIH HHS · CA42564 · United States
Databases
GENBANK
L10719
External Links
PubMed source DOI: 10.1073/pnas.90.10.4490 PMC Full Text View journal details
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