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PMID: 8127913 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 91 ·No. 5 ·1994-03-01 ·Pages 1950-4

Cairns BR, Kim YJ, Sayre MH, Laurent BC, Kornberg RD

Abstract

A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.

Related Genes
SNF5 SNF6 SW11/ADR6 SW12/SNF2 SW13
MeSH Terms
Adenosine Triphosphatases/genetics,isolation & purification Base Sequence Chromosomal Proteins, Non-Histone DNA Helicases DNA Primers/genetics DNA, Fungal/genetics DNA-Binding Proteins/genetics,isolation & purification Fungal Proteins/genetics,isolation & purification Genes, Fungal Macromolecular Substances Molecular Sequence Data Nuclear Proteins SMARCB1 Protein Saccharomyces cerevisiae/genetics Saccharomyces cerevisiae Proteins Transcription Factors/genetics,isolation & purification Transcription, Genetic
Chemicals
Chromosomal Proteins, Non-Histone DNA Primers DNA, Fungal DNA-Binding Proteins Fungal Proteins Macromolecular Substances Nuclear Proteins SMARCB1 Protein SMARCB1 protein, human SNF5 protein, S cerevisiae Saccharomyces cerevisiae Proteins Transcription Factors Adenosine Triphosphatases SNF2 protein, S cerevisiae DNA Helicases
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Cairns B R
Department of Cell Biology, Stanford University School of Medicine, CA 94305.
Kim Y J
Sayre M H
Laurent B C
Kornberg R D
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44 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.91.5.1950
Published
1994-03-01
Pages
1950-4
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC43282
Subset
IM
Grants
NIGMS NIH HHS · GM36659 · United States
External Links
PubMed source DOI: 10.1073/pnas.91.5.1950 PMC Full Text View journal details
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