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PMID: 9171430 Published · ppublish English Journal Article

Characterization of endonuclease III (nth) and endonuclease VIII (nei) mutants of Escherichia coli K-12.

Journal of bacteriology ·Vol. 179 ·No. 11 ·1997-06-00 ·Pages 3783-5

Saito Y, Uraki F, Nakajima S, Asaeda A, Ono K, Kubo K, Yamamoto K

Abstract

The nth and nei genes of Escherichia coli affect the production of endonuclease III and endonuclease VIII, respectively, glycosylases/apurinic lyases that attack DNA damaged by oxidizing agents. Here, we provide evidence that oxidative lethal lesions are repaired by both endonuclease III and endonuclease VIII and that spontaneous mutagenic lesions are repaired mainly by endonuclease III.

MeSH Terms
Cloning, Molecular Deoxyribonuclease (Pyrimidine Dimer) Endodeoxyribonucleases/genetics Escherichia coli/enzymology,genetics Escherichia coli Proteins Genes, Bacterial Molecular Sequence Data Mutation
Chemicals
Escherichia coli Proteins Endodeoxyribonucleases Deoxyribonuclease (Pyrimidine Dimer) NTH protein, E coli
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Saito Y
Biological Institute, Graduate School of Science, Tohoku University, Sendai, Japan.
Uraki F
Nakajima S
Asaeda A
Ono K
Kubo K
Yamamoto K
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.179.11.3783-3785.1997
Published
1997-06-00
Pages
3783-5
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC179178
Subset
IM
Databases
GENBANK
D89754
External Links
PubMed source DOI: 10.1128/jb.179.11.3783-3785.1997 PMC Full Text View journal details
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