Here we report a new fusion gene, STRN3-RARA, in acute promyelocytic leukemia (APL). It cooperates with UTX deficiency t...
...RARA) gene. In this study, DNA probes around the second exon of the RARA gene showed rearrangements not previously detec...
...RARA fusion gene. More than 98% of APL have PML-RARA fusion, and less than 2% have other types of RARA gene partners, wh...
...RarA protein is part of a highly conserved family of DNA metabolism proteins. We demonstrate that RarA binds to double-s...
...RARA, PML/RARA, and RARA/PML transcripts by RT-PCR and of the PML/RARA and RARA proteins by Western blotting in all the ...
...RARA fusion gene. In previous studies, we demonstrated that expression of a human PML-RARA complementary DNA in murine g...
...RARA, the initiating fusion protein for this disease. However, the underlying mechanisms by which PML-RARA initiates and...
...RARA gene rearrangements and t(5;17) that leads to the NPM/RARA fusion gene, which are retinoid-responsive, and (2) case...
Several variant RARA translocations have been reported in acute promyelocytic leukemia (APL) of which the t(11;17)(q23;q...
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