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Bacillus subtilis RarA modulates replication restart.

Carrasco(B),Seco(EM),López-Sanz(M),Alonso(JC… Nucleic Acids Res 2018-00-21

...RarA, and for such recruitment the amphipathic C-terminal domain of SsbA is required. RarA is a DNA-dependent ATPase str...

RXR is an essential component of the oncogenic PML/RARA complex in vivo.

Zhu(J),Nasr(R),Pérès(L),Riaucoux-Lormière(F)… Cancer Cell 2007-07-00

...RARA homodimerization allows PML/RARA to bind DNA independently of its coreceptor RXR, the latter was identified within ...

Diagnosis of variant RARA translocation using standard dual-color dual-fusion P…

Singh(MK),Parihar(M),Arora(N),Mishra(DK),Bha… Hematol Oncol Stem Cell Ther 2019-03-00

...RARA genes to detect PML/RARA fusions. Here, we report a case highlighting the importance of atypical FISH signal patter...

PML-RARA-RXR oligomers mediate retinoid and rexinoid/cAMP cross-talk in acute p…

Kamashev(D),Vitoux(D),De Thé(H) J Exp Med 2004-04-19

...RARA was proposed to initiate acute promyelocytic leukemia (APL) through PML-RARA homodimer-triggered repression. Here, ...

Targeting RARA overexpression with tamibarotene, a potent and selective RARα ag…

de Botton(S),Cluzeau(T),Vigil(C),Cook(RJ),Ro… Blood Adv 2023-00-09

...RARA-positive (n = 22) or RARA-negative (n = 29) for RARA mRNA overexpression in peripheral blasts using a blood-based b...

Optical Genome Mapping Reveals Complex and Cryptic Rearrangement Involving PML:…

Klausner(M),Stinnett(V),Ghabrial(J),Morsberg… Genes (Basel) 2024-10-30

...RARA fusion resulting from a cryptic and complex insertion of PML::RARA into RARA on 17q21.2 whereby a segment of 15q24....

Uncoupling RARA transcriptional activation and degradation clarifies the bases …

Ablain(J),Leiva(M),Peres(L),Fonsart(J),Antho… J Exp Med 2013-04-08

...RARA- or PML/RARA-dependent transcription, but fail to down-regulate RARA or PML/RARA protein levels. Similar to RA, the...

PML-RARA fusion resulting from a cryptic insertion of RARA gene into PML gene w…

Fan(H),Ortega(V),Fanasch(HM),Wang(Y),Holder(… Eur J Haematol 2014-10-00

...RARA transcript and lack of the reciprocal RARA-PML transcript. Although such cryptic insertions leading to a PML-RARA f...

[hCG-PLZF-RARA transgenic mice develop leukemia resembling human chronic myeloi…

Meng(X),Cheng(G),Wang(L) Zhonghua Zhong Liu Za Zhi 2000-01-00

...RARA fusion protein in vivo, hCG-PLZF-RARA transgenic mice were generated, in which PIZF-RARA fusion gene was driven by ...

Identification of a novel TNRC18-RARA fusion in acute promyelocytic leukemia la…

Wang(Z),Wen(L),Zhang(L),Xu(X),Chen(X),Yao(L)… Mol Carcinog 2021-00-00

...RARA fusion gene, which is generated by chromosomal translocation t(15;17)(q24;q21). We identified TNRC18-RARA as novel ...

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