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Absolute quantification of the pretreatment PML-RARA transcript defines the rel…

Albano(Francesco),Zagaria(Antonella),Anelli(… Oncotarget 2016-04-07

...RARA initial molecular burden. ddPCR analysis revealed that the amount of PML-RARA transcript at diagnosis in the group ...

Retinoic acid receptor alpha inhibits ferroptosis by promoting thioredoxin and …

Bian(Y),Shan(G),Liang(J),Hu(Z),Sui(Q),Shi(H)… Commun Biol 2024-00-20

...RARA) is upregulated with the treatment of ferroptosis inducers (FINs). Pharmacological activation of RARA increases the...

Syndromic chorioretinal coloboma associated with heterozygous de novo RARA muta…

Jakubiuk-Tomaszuk(A),Murcia Pienkowski(V),Zi… Clin Genet 2019-00-00

...RARA or RARG. We describe a girl with a de novo mutation NM_000964 c.826C > T (p.Arg276Trp) in RARA with symptoms overla...

The leukemic oncoprotein NPM1-RARA inhibits TP53 activity.

Swaney(Erin M),Chattopadhyay(Anuja),Abecassi… Leuk Lymphoma 0000-00-00

...RARA). We found that ectopic NPM1-RARA expression decreased TP53 protein levels in target cells. NPM1-RARA impaired TP53...

FISH Signal Pattern for an APL Variant Translocation with a PRKAR1A-RARA Fusion.

Liu(K),You(B),Duncan(J),Root(A),Zhang(H) J Assoc Genet Technol 2022-00-00

...RARA gene with an alternate gene partner, a RARA break-apart probe should be used to verify the RARA rearrangement. The ...

Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation.

Vitaliano-Prunier(A),Halftermeyer(J),Ablain(… Blood 2014-12-11

...RARA targets, how arsenic triggers differentiation remains unclear. Here we demonstrate that extinction of PML/RARA trig...

RARA fusion genes in acute promyelocytic leukemia: a review.

De Braekeleer(E),Douet-Guilbert(N),De Braeke… Expert Rev Hematol 2014-06-00

...RARA fusion gene, is the hallmark of acute promyelocytic leukemia (APL). At present, eight other genes fusing with RARA ...

LncRNA RARA-AS1 could serve as a novel prognostic biomarker in pan-cancer and p…

Huang(Y),Deng(S),Jiang(Q),Shi(J) Sci Rep 2023-00-13

...RARA Antisense RNA 1 (RARA-AS1) in cancer and its implications for diagnosis and treatment. Various bioinformatics tools...

Acute promyelocytic leukemia with a cryptic insertion of RARA into TBL1XR1.

Osumi(T),Watanabe(A),Okamura(K),Nakabayashi(… Genes Chromosomes Cancer 2019-00-00

...RARA gene. The TBL1XR1-RARA fusion gene has recently been reported as a novel RARA-associated fusion gene. We report a c...

Potential functions of retinoic acid receptor A in Sertoli cells and germ cells…

Doyle(TJ),Braun(KW),McLean(DJ),Wright(RW),Gr… Ann N Y Acad Sci 2007-12-00

...Rara) knockout male mice. The seminiferous tubules of Rara knockout mice showed varying degrees of germ-cell degeneratio...

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