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PMID: 11325979 Published · ppublish English Journal Article

Genetic diversity of Neisseria lactamica strains from epidemiologically defined carriers.

Journal of clinical microbiology ·Vol. 39 ·No. 5 ·2001-05-00 ·Pages 1710-5

Alber D, Oberkötter M, Suerbaum S, Claus H, Frosch M, Vogel U

Abstract

We assessed the genetic diversity of 26 Neisseria lactamica strains from epidemiologically related sources, i.e., groups of kindergartens and primary schools in three Bavarian towns, by the partial sequencing of the argF, rho, recA, and 16S ribosomal genes. We found a total of 17 genotypes, of which 12 were found only in one strain. The genotypes comprised 5 alleles of the argF gene, 9 of rho, 8 of recA, and 10 of the 16S ribosomal DNA. Sequence analysis by determination of homoplasy ratios and split decomposition analysis revealed abundant recombination within N. lactamica.

MeSH Terms
Bacterial Proteins/genetics Base Sequence Carrier State/epidemiology,microbiology Child Child, Preschool Genes, Bacterial Genes, rRNA/genetics Genetic Variation Genotype Humans Meningococcal Infections/epidemiology,microbiology Molecular Sequence Data Nasopharynx/microbiology Neisseria/classification,genetics,immunology Neisseria meningitidis/classification,genetics RNA, Ribosomal, 16S/genetics Recombination, Genetic Sequence Analysis, DNA
Chemicals
Bacterial Proteins RNA, Ribosomal, 16S
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Alber D
Institut für Hygiene und Mikrobiologie, Universität Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany.
Oberkötter M
Suerbaum S
Claus H
Frosch M
Vogel U
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Article Info
Journal
Journal of clinical microbiology
Abbr.
J Clin Microbiol
ISSN
0095-1137
DOI
10.1128/JCM.39.5.1710-1715.2001
Published
2001-05-00
Pages
1710-5
Language
English
Region
United States
NLM ID
7505564
PMCID
PMC88014
Subset
IM
External Links
PubMed source DOI: 10.1128/JCM.39.5.1710-1715.2001 PMC Full Text View journal details
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