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PMID: 1752413 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

New SNF genes, GAL11 and GRR1 affect SUC2 expression in Saccharomyces cerevisiae.

Genetics ·Vol. 129 ·No. 3 ·1991-11-00 ·Pages 675-84

Vallier LG, Carlson M

Abstract

To identify new genes required for depression of the SUC2 (invertase) gene in Saccharomyces cerevisiae, we have isolated mutants with defects in raffinose utilization. In addition to mutations in SUC2 and previously identified SNF genes, we recovered recessive mutations that define four new complementation groups, designated snf7 through snf10. These mutations cause defects in the derepression of SUC2 in response to glucose limitation. We also recovered five alleles of gal11 and showed that a gal11 null mutation decreases SUC2 expression to 30% of the wild-type level. Finally, one of the mutants carries a grr1 allele that converts SUC2 from a glucose-inducible gene.

Related Genes
GAL11 SNF10 SNF7 SNF8 SNF9 SUC2 grr1
MeSH Terms
Alleles Chromosome Mapping Enzyme Repression Gene Expression Regulation, Fungal Genes, Fungal Genetic Complementation Test Glucose/metabolism Glycoside Hydrolases/genetics,metabolism Saccharomyces cerevisiae/genetics Sucrose/metabolism beta-Fructofuranosidase
Chemicals
Sucrose Glycoside Hydrolases beta-Fructofuranosidase Glucose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Vallier L G
Department of Genetics and Development, Columbia University College of Physicians and Surgeons, New York, New York 10032.
Carlson M
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/129.3.675
Published
1991-11-00
Pages
675-84
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1204735
Subset
IM
Grants
NIGMS NIH HHS · GM34095 · United States
External Links
PubMed source DOI: 10.1093/genetics/129.3.675 PMC Full Text View journal details
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