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PMID: 22772908 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Genes for plant autophagy: functions and interactions.

Molecules and cells ·Vol. 34 ·No. 5 ·2012-11-00 ·Pages 413-23

Kim SH, Kwon C, Lee JH, Chung T

Abstract

Autophagy, or self-consuming of cytoplasmic constituents in a lytic compartment, plays a crucial role in nutrient recycling, development, cell homeostasis, and defense against pathogens and toxic products. Autophagy in plant cells uses a conserved machinery of core Autophagy-related (Atg) proteins. Recently, research on plant autophagy has been expanding and other components interacting with the core Atg proteins are being revealed. In addition, growing evidence suggests that autophagy communicates with other cellular pathways such as the ubiquitin-proteasome system, protein secretory pathway, and endocytic pathway. An increase in our understanding of plant autophagy will undoubtedly help test the hypothesized functions of plant autophagy in programmed cell death, vacuole biogenesis, and responses to biotic, abiotic, and nutritional stresses. In this review, we summarize recent progress on these topics and suggest topics for future research, after inspecting common phenotypes of current Arabidopsis atg mutants.

MeSH Terms
Arabidopsis/genetics,metabolism Arabidopsis Proteins/genetics,metabolism Autophagy/genetics Gene Expression Regulation, Plant Models, Biological Ubiquitin/genetics,metabolism Vesicular Transport Proteins/genetics,metabolism
Chemicals
Arabidopsis Proteins Ubiquitin Vesicular Transport Proteins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Kim Soon-Hee
Department of Biological Sciences, Pusan National University, Busan, 609-735, Korea.
Kwon Chian
Lee Jae-Hoon
Chung Taijoon
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Article Info
Journal
Molecules and cells
Abbr.
Mol Cells
ISSN
0219-1032
DOI
10.1007/s10059-012-0098-y
Published
2012-11-00
Epub
2012-00-06
Pages
413-23
Language
English
Region
Korea (South)
NLM ID
9610936
PMCID
PMC3887786
Subset
IM
External Links
PubMed source DOI: 10.1007/s10059-012-0098-y PMC Full Text View journal details
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