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PMID: 2866091 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Structure of the murine Thy-1 gene.

The EMBO journal ·Vol. 4 ·No. 8 ·1985-08-00 ·Pages 2017-24

Giguére V, Isobe K, Grosveld F

Abstract

We have cloned the murine Thy-1.1 (AKR) and Thy-1.2 (Balb/c) genes. The complete exon/intron structure and the nucleotide sequence of the Thy-1.2 gene was determined. The gene contains four exons and three intervening sequences. The complete transcriptional unit gives rise to a tissue and developmental stage-specific mRNA of 1850 bp. The 5' end of the gene has multiple initiation sites and a non-TATA box promoter. The 3' end shows a single polyadenylation site after a very long untranslated region.

MeSH Terms
Amino Acid Sequence Animals Antigens, Surface/genetics Base Sequence Cloning, Molecular DNA/analysis DNA Restriction Enzymes Genes HeLa Cells Humans Mice Mice, Inbred Strains Plasmids RNA, Messenger/genetics Rats Species Specificity Thy-1 Antigens Transcription, Genetic Transfection
Chemicals
Antigens, Surface RNA, Messenger Thy-1 Antigens DNA DNA Restriction Enzymes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Giguére V
Isobe K
Grosveld F
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44 references, click to expand
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Article Info
Journal
The EMBO journal
Abbr.
EMBO J
ISSN
0261-4189
Published
1985-08-00
Pages
2017-24
Language
English
Region
England
NLM ID
8208664
PMCID
PMC554456
Subset
IM
Databases
GENBANK
X02772
External Links
PubMed source PMC Full Text View journal details
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