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PMID: 6157327 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Immune complexes in human diseases: a review.

The American journal of pathology ·Vol. 100 ·No. 2 ·1980-08-00 ·Pages 529-94

Theofilopoulos AN, Dixon FJ

Abstract

暂无摘要

MeSH Terms
Animals Antibody Formation Antigen-Antibody Complex Arthritis, Rheumatoid/immunology Autoimmune Diseases/immunology Bacterial Infections/immunology Complement Activation Epitopes Glomerulonephritis/immunology Hepatitis, Viral, Human/immunology Humans Immune Complex Diseases/immunology Immunologic Techniques Lupus Erythematosus, Systemic/immunology Neoplasms/immunology Parasitic Diseases/immunology Receptors, Immunologic/metabolism Virus Diseases/immunology
Chemicals
Antigen-Antibody Complex Epitopes Receptors, Immunologic
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Theofilopoulos A N
Dixon F J
References (409)
409 references, click to expand
  1. Circulating immune complexes in serum from patients with dengue haemorrhagic fever.
    Clin Exp Immunol. 1979 Apr;36(1):46-53 PMID: 380857
  2. Inhibition of spontaneous and antibody-dependent cellular cytotoxicity by sera and isolated antiglobulin preparations from rheumatoid arthritis patients.
    Scand J Immunol. 1977;6(3):173-83 PMID: 300499
  3. The C1q binding test for soluble immune complexes: clinical correlations obtained in patients with cancer.
    J Natl Cancer Inst. 1977 May;58(5):1205-15 PMID: 323505
  4. Characterization of immune complexes in serum by adsorption on staphylococcal protein A: model studies and application to sera of rats bearing a gross virus-induced lymphoma.
    J Immunol. 1978 Nov;121(5):1644-51 PMID: 712061
  5. Chronic membranous glomerulonephritis caused by hepatitis B antigen-antibody immune complexes.
    Ann Intern Med. 1974 Oct;81(4):448-51 PMID: 4212994
  6. Detection of immune complexes.
    J Invest Dermatol. 1976 Sep;67(3):339-45 PMID: 823267
  7. A simple method of Rh determination.
    Nature. 1956 Sep 8;178(4532):539 PMID: 13358793
  8. The molecular basis of self-association of antibodies to IgG (rheumatoid factors) in rheumatoid arthritis.
    Proc Natl Acad Sci U S A. 1974 Feb;71(2):517-21 PMID: 4131277
  9. Detection of circulating IgG aggregates and immune complexes using 125I protein A from Staphylococcus aureus.
    Ann Rheum Dis. 1976 Aug;35(4):306-13 PMID: 788651
  10. Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness.
    J Immunol. 1970 Aug;105(2):279-90 PMID: 4194303
  11. Antibody-enhanced dengue virus infection in primate leukocytes.
    Nature. 1977 Feb 24;265(5596):739-41 PMID: 404559
  12. THE INTERACTION BETWEEN POLYSACCHARIDES AND OTHER MACROMOLECULES. 5. THE SOLUBILITY OF PROTEINS IN THE PRESENCE OF DEXTRAN.
    Biochem J. 1963 Nov;89:253-7 PMID: 14084609
  13. Lymphocyte-mediated cytotoxicity and blocking serum activity to tumor antigens.
    Adv Immunol. 1974;18:209-77 PMID: 4597622
  14. Lymphocytotoxic antibody activity in cryoprecipitates from serum of patients with SLE.
    Arthritis Rheum. 1976 Sep-Oct;19(5):844-50 PMID: 1085625
  15. Correlation between immune complexes and prognostic factors in Hodgkin's disease.
    Clin Exp Immunol. 1978 Feb;31(2):166-73 PMID: 648026
  16. Viral type A and type B hepatitis: morphology, biology, immunology and epidemiology--a review.
    Am J Clin Pathol. 1976 May;65(5 Suppl):741-86 PMID: 218439
  17. Circulating immune complexes in acute schistosomiasis.
    Clin Exp Immunol. 1979 Aug;37(2):221-7 PMID: 498584
  18. Rat spleen leucocyte (RSL) radioimmunoassay for the detection and quantification of soluble immune complexes.
    Clin Exp Immunol. 1978 Dec;34(3):429-35 PMID: 105829
  19. Immune complexes in sera and synovial fluids of patients with rheumatoid arthritis. Radioimmunoassay with monocylonal rheumatoid factor.
    J Clin Invest. 1975 Aug;56(2):458-66 PMID: 125289
  20. Plasmapheresis in the management of acute systemic lupus erythematosus?
    Lancet. 1976 Apr 3;1(7962):709-11 PMID: 56531
  21. Immunofluorescent demonstration of an IgG-B1C complex in synovial lining cells of rheumatoid synovial membrane.
    Clin Exp Immunol. 1969 Feb;4(2):265-71 PMID: 4892526
  22. Binding of immunoglobulin G aggregates and immune complexes in human sera to Staphylococci containing protein A.
    J Clin Invest. 1979 Apr;63(4):627-36 PMID: 438327
  23. A method of trace iodination of proteins for immunologic studies.
    Int Arch Allergy Appl Immunol. 1966;29(2):185-9 PMID: 4160044
  24. Study of cutaneous lupus erythematosus by immunohistochemical methods.
    Arch Dermatol. 1968 May;97(5):520-6 PMID: 4171670
  25. Quantitation of immune complexes by nephelometry.
    J Immunol Methods. 1979;29(3):237-44 PMID: 489992
  26. Cryoimmunoglobulinemia in rheumatoid arthritis. Significance in serum of patients with rheumatoid vasculitis.
    J Clin Invest. 1975 Sep;56(3):725-39 PMID: 169295
  27. Detection of immune complexes in unheated sera by modified 125I-Clq binding test. Effect of heating on the binding of Clq by immune complexes and application of the test to systemic lupus erythematosus.
    J Immunol. 1976 Jan;116(1):232-5 PMID: 1245740
  28. Studies into the occurrence of soluble antigen--antibody complexes in disease. I. A biological assay for soluble complexes.
    Clin Exp Immunol. 1968 Jul;3(6):525-36 PMID: 4178230
  29. Breakdown products of C 3 in human synovial fluids.
    J Clin Invest. 1969 Aug;48(8):1532-42 PMID: 4183680
  30. Serum-serum interactions in autoimmune mice.
    Arthritis Rheum. 1979 Oct;22(10):1074-81 PMID: 158362
  31. Detection and characterization of circulating immune complexes by ultracentrifugation. Technical aspects.
    J Immunol Methods. 1979;26(2):99-112 PMID: 35570
  32. Detection and radioassay of soluble circulating immune complexes using guinea pig peritoneal exudate cells.
    Nature. 1974 Mar 8;248(5444):156-9 PMID: 4132041
  33. IgM rheumatoid factor and low molecular weight IgM. An association with vasculitis.
    Arthritis Rheum. 1974 May-Jun;17(3):272-84 PMID: 4825647
  34. Antibody-dependent cell-mediated cytotoxicity in selected autoimmune diseases.
    J Clin Invest. 1976 Jul;58(1):173-9 PMID: 6490
  35. Circulating immune complexes in steroid-responsive nephrotic syndrome.
    N Engl J Med. 1978 Jan 19;298(3):126-9 PMID: 619241
  36. In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus.
    J Exp Med. 1976 Aug 1;144(2):428-43 PMID: 8578
  37. Serum immune complexes in membranoproliferative and other glomerulonephritides.
    Kidney Int. 1977 Apr;11(4):275-83 PMID: 853604
  38. Rheumatoid synovitis. An extravascular immune complex disease.
    Arthritis Rheum. 1974 May-Jun;17(3):297-305 PMID: 4274943
  39. Renal morphological and immunological changes associated with acute viral hepatitis.
    Kidney Int. 1972 Jun;1(6):413-9 PMID: 4365635
  40. Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.
    J Exp Med. 1978 Nov 1;148(5):1198-215 PMID: 309911
  41. HBsAg immune complexes in the course of infection with hepatitis B virus.
    Clin Exp Immunol. 1979 Jun;36(3):371-8 PMID: 487641
  42. The role of complement, immunoglobulin and bacterial antigen in coagulase-negative staphylococcal shunt nephritis.
    Am J Med. 1975 Nov;59(5):660-73 PMID: 1106192
  43. Rheumatoid arthritis. Biosynthesis of complement proteins by synovial tissues.
    N Engl J Med. 1974 Jun 6;290(23):1284-8 PMID: 4133295
  44. The immune complex glomerulonephritis of bacterial endocarditis.
    Medicine (Baltimore). 1972 Jan;51(1):1-25 PMID: 4550571
  45. Allergic complications of meningococcal disease. II. Immunological investigations.
    Br Med J. 1973 Jun 30;2(5869):737-40 PMID: 4268767
  46. The specificity and polyvalency of binding of a monoclonal rheumatoid factor.
    Immunochemistry. 1976 Apr;13(4):355-9 PMID: 59692
  47. The biology and detection of immune complexes.
    Adv Immunol. 1979;28:89-220 PMID: 94506
  48. Circulating immune complexes in inflammatory bowel disease.
    Clin Exp Immunol. 1973 Jun;14(2):219-26 PMID: 4197968
  49. Pathogenesis of renal disease associated with viral hepatitis.
    Arch Pathol. 1974 Apr;97(4):193-200 PMID: 4273591
  50. Damaged membrane fragments and immune complexes in the blood of patients with Behcet's syndrome.
    Clin Exp Immunol. 1978 Nov;34(2):206-12 PMID: 737904
  51. Circulating immune complexes in ulcerative colitis.--II. Correlation with serum protein concentrations and complement conversion products.
    Clin Exp Immunol. 1978 Jan;31(1):81-91 PMID: 639352
  52. Survey for immune complexes in disseminated gonococcal arthritis-dermatitis syndrome.
    Arthritis Rheum. 1979 Jan;22(1):19-24 PMID: 153144
  53. Glomerulonephritis with deposition of Australia antigen-antibody complexes in glomerular basement membrane.
    Lancet. 1971 Jul 31;2(7718):234-7 PMID: 4104770
  54. THE ROLE OF ANTIGEN-ANTIBODY COMPLEXES IN DISEASE.
    Harvey Lect. 1963;58:21-52 PMID: 14272577
  55. C1g precipitins in the sera of patients with systemic lupus erythematosus and other hypocomplementemic states: characterization of high and low molecular weight types.
    J Exp Med. 1971 Sep 1;134(3 Pt 2):228s-241s PMID: 4998931
  56. Natural thymocytotoxic autoantibody and reactive antigen in New Zealand black and other mice.
    Proc Natl Acad Sci U S A. 1971 Jul;68(7):1412-5 PMID: 5283928
  57. Receptors for immune complexes on lymphocytes.
    Adv Immunol. 1974;19(0):217-58 PMID: 4611172
  58. Rheumatoid factor, complement, and conglutinin aberrations in patients with subacute bacterial endocarditis.
    J Clin Invest. 1962 Mar;41:666-75 PMID: 14007218
  59. Role of immune complexes involving SH antigen in pathogenesis of chronic active hepatitis and polyarteritis nodosa.
    Lancet. 1971 Jun 26;1(7713):1309-12 PMID: 4103392
  60. Autoimmune response to DNA, red blood cells, and thymocyte antigens in association with polyclonal antibody synthesis during experimental African trypanosomiasis.
    J Immunol. 1979 Jan;122(1):296-301 PMID: 310833
  61. Pathogenesis of serum sickness.
    AMA Arch Pathol. 1958 Jan;65(1):18-28 PMID: 13487025
  62. Circulating immune complexes in pre-eclampsia.
    Br Med J. 1978 Jun 3;1(6125):1450-1 PMID: 647331
  63. Polyarthritis, polyarteritis and hepatitis B.
    Medicine (Baltimore). 1976 Jan;55(1):19-37 PMID: 1629
  64. Australia antigen-antibody complexes.
    Nature. 1970 Apr 4;226(5240):83-4 PMID: 4985010
  65. Complexed IgE in atopy.
    Lancet. 1977 Oct 8;2(8041):741-2 PMID: 71544
  66. Replication of dengue-2 virus in cultured human lymphoblastoid cells and subpopulations of human peripheral leukocytes.
    J Immunol. 1976 Sep;117(3):953-61 PMID: 1085314
  67. Quantitation of acute and chronic serum sickness in the rabbit.
    J Exp Med. 1971 Sep 1;134(3 Pt 2):7s-8s PMID: 5570757
  68. Studies of cryoproteins in systemic lupus erythematosus.
    J Clin Invest. 1967 Mar;46(3):400-8 PMID: 4164677
  69. Association between hepatitis B virus and essential mixed cryoglobulinemia.
    N Engl J Med. 1977 Jun 30;296(26):1501-4 PMID: 865530
  70. The nature of immune complexes in human cancer sera.
    J Immunol. 1977 Aug;119(2):657-63 PMID: 886189
  71. Systemic lupus erythematosus. Cryoprecipitation of sera.
    J Clin Invest. 1963 Jun;42:823-9 PMID: 14021124
  72. Viral hepatitis, type B (MS-2-strain). Further observations on natural history and prevention.
    N Engl J Med. 1973 Apr 12;288(15):755-60 PMID: 4688714
  73. The immunopathology of joint inflammation in rheumatoid arthritis.
    Adv Immunol. 1973;16(0):265-336 PMID: 4599390
  74. Detection of immune complexes in acute rheumatic fever and their relationship to HLA-B5.
    J Clin Invest. 1980 Jan;65(1):136-45 PMID: 6765956
  75. Arthritis of hepatitis associated with Australia antigen.
    Ann Intern Med. 1971 Jul;75(1):29-33 PMID: 5091564
  76. Isolation of a thermolabile serum protein which precipitates gamma-globulin aggregates and participates in immune hemolysis.
    Proc Soc Exp Biol Med. 1961 Feb;106:291-5 PMID: 13726743
  77. IgG rheumatoid factor in subacute bacterial endocarditis: relationship to IgM rheumatoid factor and circulating immune complexes.
    Clin Exp Immunol. 1978 Jan;31(1):100-3 PMID: 639341
  78. Acute glomerulonephritis associated with varicella infection.
    Am J Med. 1968 Mar;44(3):489-92 PMID: 5641309
  79. Immune complexes in glomeruli of patients with leprosy.
    Lepr Rev. 1971 Dec;42(4):282-9 PMID: 4263088
  80. Circulating immune complexes in Lyme arthritis. Detection by the 125I-C1q binding, C1q solid phase, and Raji cell assays.
    J Clin Invest. 1979 Mar;63(3):468-77 PMID: 429566
  81. Serum immunoglobulins, complement component levels and autoantibodies in liver disease.
    Clin Exp Immunol. 1973 Jul;14(3):335-46 PMID: 4199089
  82. Thyroglobulin-anti-thyroglobulin immune complex glomerulonephritis complicating radioiodine therapy.
    Clin Immunol Immunopathol. 1978 Mar;9(3):327-34 PMID: 342161
  83. Infectious virus-antibody complex in the blood of chronically infected mice.
    J Exp Med. 1966 Jul 1;124(1):81-97 PMID: 5944351
  84. Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis.
    J Clin Invest. 1975 Jul;56(1):165-76 PMID: 1141431
  85. Immune complexes in acute and chronic liver disease.
    Clin Exp Immunol. 1978 Feb;31(2):150-7 PMID: 648025
  86. Immune complex-mediated glomerulonephritis with infectious mononucleosis.
    Aust N Z J Med. 1974 Apr;4(2):192-5 PMID: 4278133
  87. HEMOLYTIC COMPLEMENT IN SYNOVIAL FLUID.
    J Clin Invest. 1964 Jul;43:1372-82 PMID: 14192518
  88. The development of HBsAg-positive hepatitis despite the previous existence of antibody to HBsAg.
    J Immunol. 1976 Dec;117(6):2260-2 PMID: 993599
  89. A nephelometric study of the reaction of monoclonal rheumatoid factor with heat aggregated gamma globulin and sera from patients with immune complex diseases.
    Clin Exp Immunol. 1979 Sep;37(3):408-15 PMID: 92379
  90. Clinical relevance of circulating immune complexes in human leukemia. Association in acute leukemia of the presence of immune complexes with unfavorable prognosis.
    J Clin Invest. 1977 Oct;60(4):874-84 PMID: 268330
  91. Serum beta-1C globulin in glomerulonephritis and systemic lupus erythematosus.
    Ann Intern Med. 1969 Aug;71(2):327-33 PMID: 4184993
  92. Complement and immunoconglutinin changes in the nephrotic syndrome of adult Africans.
    J Trop Med Hyg. 1970 Oct;73(10):250-4 PMID: 5478040
  93. A search for antigen-antibody complexes in pre-eclampsia: further evidence against immunologic pathogenesis.
    Am J Obstet Gynecol. 1978 Sep 1;132(1):87-9 PMID: 696791
  94. Dengue viruses and mononuclear phagocytes. II. Identity of blood and tissue leukocytes supporting in vitro infection.
    J Exp Med. 1977 Jul 1;146(1):218-29 PMID: 195000
  95. Localization of fluorescein-labeled antinucleoside antibodies in glomeruli of patients with active systemic lupus erythematosus nephritis.
    J Clin Invest. 1970 Nov;49(11):2106-18 PMID: 4097660
  96. Suppressor function of peripheral blood mononuclear cells in normal individuals and in patients with systemic lupus erythematosus.
    J Clin Invest. 1977 Jan;59(1):106-16 PMID: 830659
  97. Association between an HLA haplotype and low responsiveness to tetanus toxoid in man.
    Nature. 1978 Mar 23;272(5651):359-61 PMID: 76289
  98. Immunological studies concerning the nephritis of systemic lupus erythematosus.
    J Exp Med. 1967 Oct 1;126(4):607-24 PMID: 4168098
  99. Nephrotic syndrome associated with bacteraemia after shunt operations for hydrocephalus.
    Lancet. 1965 Nov 6;2(7419):921-4 PMID: 4165274
  100. Exogenous immunoglobulin and the macrophage origin of Reed-Sternberg cells in Hodgkin's disease.
    N Engl J Med. 1978 Nov 30;299(22):1208-14 PMID: 101841
  101. Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis. Partial characterization and relationship to lowered complement levels.
    Clin Exp Immunol. 1970 May;6(5):689-706 PMID: 4097828
  102. Competition for receptors for immunoglobulin on cytotoxic lymphocytes.
    Clin Exp Immunol. 1972 Feb;10(2):275-83 PMID: 4340032
  103. Immune complexes in congenital and natal cytomegalovirus infections of man.
    J Clin Invest. 1977 Oct;60(4):838-45 PMID: 197126
  104. The relationships between the chemical nature of the antigen, antigen dosage, rate of antibody synthesis and the occurrence of arteritis and glomerulonephritis in experimental hypersensitivity.
    Bull Johns Hopkins Hosp. 1957 Sep;101(3):149-69 PMID: 13460553
  105. Immune complexes in rheumatoid arthritis sera and synovial fluids: a comparison of three methods.
    Arthritis Rheum. 1979 May;22(5):440-8 PMID: 444313
  106. Demonstration and quantitation of activation of the first component of complement in human serum.
    J Exp Med. 1978 Feb 1;147(2):385-95 PMID: 75238
  107. Sequential changes of serum complement in HAA related arthritis.
    N Engl J Med. 1972 Jul 13;287(2):103 PMID: 5031382
  108. Systemic lupus erythematosus: prototype of immune complex nephritis in man.
    J Exp Med. 1971 Sep 1;134(3 Pt 2):169s-179s PMID: 4936811
  109. Presence of anti-Sm reactivity in autoimmune mouse strains.
    J Exp Med. 1978 Feb 1;147(2):582-7 PMID: 304883
  110. Characterization of the gamma-globulin complexes present in certain sera having high titers of anti-gamma-globulin activity.
    J Clin Invest. 1966 Apr;45(4):501-12 PMID: 4957008
  111. Capacity of complement c3 phenotypes to bind on to mononuclear cells in man.
    Nature. 1974 Oct 25;251(5477):740-1 PMID: 4427677
  112. Circulating immune complexes in sera from patients receiving procainamide.
    Clin Immunol Immunopathol. 1979 Feb;12(2):220-7 PMID: 311265
  113. Glomerulonephritis associated with hepatitis-B surface antigen immune complexes in children.
    Lancet. 1974 Aug 31;2(7879):477-82 PMID: 4136754
  114. IgA immune complexes in Henoch-Schönlein purpura.
    Lancet. 1979 Nov 24;2(8152):1100-3 PMID: 91839
  115. Immunofluorescent staining of the surfaces of lymphocytes in suspension from patients with dengue hemorrhagic fever.
    Am J Pathol. 1976 Oct;85(1):37-48 PMID: 61729
  116. Antibody-dependent eosinophil-mediated damage to 51Cr-labeled schistosomula of Schistosoma mansoni: damage by purieid eosinophils.
    J Exp Med. 1977 Jan 1;145(1):136-50 PMID: 830787
  117. Aggregation of human blood platelets by immune complexes in the sedimentation pattern test.
    Scand J Haematol Suppl. 1973;19:1-56 PMID: 4127837
  118. Immune complexes in the nephrotic syndrome of African children.
    Lancet. 1969 Jun 21;1(7608):1232-8 PMID: 4182413
  119. Cold-insoluble complexes and complement levels in systemic lupus erythematosus.
    N Engl J Med. 1969 Jun 19;280(25):1376-81 PMID: 4181609
  120. An immunofluorescent study of the skin lesions in systemic lupus erythematosus.
    Arthritis Rheum. 1966 Feb;9(1):37-46 PMID: 4143707
  121. Circulating immune complexes in schistosomiasis due to Schistosoma mansoni.
    Br Med J. 1975 May 31;2(5969):476-7 PMID: 238712
  122. Loss of suppressor T-lymphocyte function in patients with systemic lupus erythematosus (SLE).
    Clin Exp Immunol. 1978 Apr;32(1):125-33 PMID: 352583
  123. Lymphocyte transformation in human Plasmodium falciparum malaria.
    J Immunol. 1974 Aug;113(2):449-54 PMID: 4210880
  124. The role of circulating hepatitis B antigen/antibody immune complexes in the pathogenesis of vascular and hepatic manifestations in polyarteritis nodosa.
    J Clin Pathol. 1974 Nov;27(11):863-8 PMID: 4155412
  125. Immunofluorescent localization of coxsackievirus B antigen in the kidney observed at routine autopsy.
    Am J Med. 1969 Jul;47(1):36-42 PMID: 4893833
  126. Detection of circulating immune complexes by the inhibition of anti-antibody.
    Clin Immunol Immunopathol. 1978 Apr;9(4):425-35 PMID: 348365
  127. Circulating immune complexes in disseminated gonorrheal infection.
    Ann Intern Med. 1978 Jul;89(1):28-33 PMID: 666182
  128. Circulating immune complexes in schistosomiasis.
    Immunology. 1977 Jul;33(1):17-22 PMID: 873574
  129. Evidence for a malaria mitogen in human malaria.
    Nature. 1975 Oct 16;257(5527):592-4 PMID: 1101075
  130. Evidence for immune complexes involving anti-lymphocyte antibodies associated with hypocomplementaemia in chronic lymphocytic leukaemia (CLL).
    Clin Exp Immunol. 1976 Nov;26(2):189-95 PMID: 136325
  131. Receptor for soluble C3 and C3b on human lymphoblastoid (RAJI) cells. Properties and biologocal significance.
    J Exp Med. 1974 Mar 1;139(3):696-711 PMID: 4591176
  132. Direct demonstration and quantitation of the first complement component in human serum.
    Science. 1978 Mar 10;199(4333):1080-2 PMID: 75568
  133. An evaluation of elution techniques in the study of immune complex glomerulonephritis.
    J Immunol. 1977 May;118(5):1788-94 PMID: 16060
  134. Antibody-dependent direct cytotoxicity of human lymphocytes. I. Studies on peripheral blood lymphocytes and sera of patients with systemic lupus erythematosus.
    Clin Exp Immunol. 1976 May;24(2):317-22 PMID: 1084243
  135. Circulating immune complexes in patients with malignant lymphomas and solid tumors.
    Int J Cancer. 1977 Dec 15;20(6):887-94 PMID: 338514
  136. Detection of immune complexes by a new assay, the polyethylene glycol precipitation-complement consumption test (PEG-CC).
    Clin Exp Immunol. 1979 Apr;36(1):117-29 PMID: 111880
  137. Failure to detect circulating DNA--anti-DNA complexes by four radioimmunological methods in patients with systemic lupus erythematosus.
    Clin Exp Immunol. 1977 Dec;30(3):384-92 PMID: 606451
  138. Biologic and clinical significance of cryoglobulins. A report of 86 cases.
    Am J Med. 1974 Nov;57(5):775-88 PMID: 4216269
  139. Measurement of immune complexes in insulin-treated diabetics.
    J Immunol Methods. 1973 Dec;3(4):337-45 PMID: 4591347
  140. Experimental glomerulonephritis induced by in situ formation of immune complexes in glomerular capillary wall.
    Kidney Int. 1979 Aug;16(2):148-57 PMID: 390217
  141. Lymphocyte receptors for immunoglobulin.
    Adv Immunol. 1976;24:167-214 PMID: 798474
  142. Detection and characterization of DNA-anti-DNA complexes in a patient with systemic lupus erythematosus.
    Clin Exp Immunol. 1977 Jun;28(3):433-6 PMID: 302166
  143. Determination of cryoglobulins as lipoprotein-autoantibody immune complexes and antigenic determinants against antilipoprotein autoantibody.
    Clin Exp Immunol. 1977 Jun;28(3):437-44 PMID: 70290
  144. Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus.
    J Exp Med. 1979 May 1;149(5):1099-116 PMID: 221610
  145. Human C4-binding protein. Association with immune complexes in vitro and in vivo.
    J Clin Invest. 1979 Mar;63(3):437-42 PMID: 155077
  146. Degenerative vascular disease and myocardial infarction in mice with lupus-like syndrome.
    Am J Pathol. 1979 Aug;96(2):477-92 PMID: 474707
  147. Binding of circulating immune complexes to human peripheral blood lymphocytes: effect of complement.
    Clin Immunol Immunopathol. 1978 Jun;10(2):202-13 PMID: 668215
  148. C1q deviation test for the detection of immune complexes, aggregates of IgG, and bacterial products in human serum.
    J Exp Med. 1975 Jul 1;142(1):139-50 PMID: 1097571
  149. IgG complexes in serum of rheumatoid arthritis patients.
    Scand J Immunol. 1974;3(3):229-36 PMID: 4136795
  150. A Clq immunosorbent assay compared with thin-layer gel filtration for measuring IgG aggregates.
    Scand J Immunol. 1976;5(3):293-8 PMID: 1273518
  151. Circulating soluble antigens and antibody in schistosomiasis.
    Br Med J. 1975 Feb 22;1(5955):435-6 PMID: 123165
  152. Cutaneous vessel immune deposits in rheumatoid arthritis.
    Arthritis Rheum. 1976 Jan-Feb;19(1):15-20 PMID: 1082751
  153. Purification of soluble immune complexes from serum using polymethylmetacrylate beads coated with conglutinin or C1q. Application to the analysis of the components of in vitro formed immune complexes and of immune complexes occurring in vivo during leishmaniasis.
    Clin Exp Immunol. 1979 Aug;37(2):295-309 PMID: 498587
  154. Antigen-specific detection of HBsAG-containing immune complexes in the course of hepatitis B virus infection.
    Clin Exp Immunol. 1979 Aug;37(2):376-80 PMID: 91465
  155. Circulating immune complexes in normal pregnant women and in some conditions complicating pregnancy.
    Clin Exp Immunol. 1979 Jul;37(1):33-7 PMID: 487656
  156. Cryoimmunoglobulinaemia in patients with primary renal disease and systemic lupus erythematosus. I. IgG- and DNA-binding assessed by co-precipitation.
    Clin Exp Immunol. 1978 Jan;31(1):131-40 PMID: 639345
  157. Increased C1q binding immune complexes in Felty's syndrome: comparison with uncomplicated rheumatoid arthritis.
    Arthritis Rheum. 1979 Jul;22(7):697-702 PMID: 454498
  158. Serum and synovial fluid inhibitors of antibody-mediated lymphocytotoxicity in rheumatoid arthritis and systemic lupus erythematosus.
    Arthritis Rheum. 1976 Mar-Apr;19(2):142-9 PMID: 56939
  159. Identification of the platelet activating activity in rheumatoid synovial fluid as an intermediate molecular weight complex of IgG.
    J Immunol. 1979 Feb;122(2):703-9 PMID: 105050
  160. Evidence for circulating immune complexes in lepromatous leprosy.
    Lancet. 1972 Sep 16;2(7777):572-3 PMID: 4115742
  161. The occurrence of cryoproteins in synovial fluid; the association of a complement-fixing activity in rheumatoid synovial fluid with cold-precipitable protein.
    J Clin Invest. 1971 Feb;50(2):282-93 PMID: 4992991
  162. The alternative pathway of complement activation.
    Adv Immunol. 1976;24:1-35 PMID: 798473
  163. The detection of circulating immune complexes in children with recurrent infections and their treatment with human immunoglobulins.
    Clin Exp Immunol. 1977 Sep;29(3):385-92 PMID: 589860
  164. Presence of C1q-reactive immune complexes in patients with leprosy.
    Clin Exp Immunol. 1972 Oct;12(2):215-23 PMID: 4630778
  165. Characterization of IgG complexes in eluates from rheumatoid tissue.
    Clin Exp Immunol. 1971 Feb;8(2):249-62 PMID: 4929776
  166. Circulating immune complexes in patients with breast cancer.
    Br Med J. 1977 Jul 23;2(6081):218-20 PMID: 884444
  167. Circulating immune complexes in active Behçet's disease.
    Clin Exp Immunol. 1978 Nov;34(2):213-8 PMID: 737905
  168. Comparative serial virologic and serologic studies of symptomatic and subclinical congenitally and natally acquired cytomegalovirus infections.
    J Infect Dis. 1975 Nov;132(5):568-77 PMID: 171322
  169. Natural thymocytotoxic autoantibodies in autoimmune and normal mice.
    J Immunol. 1979 Jun;122(6):2272-8 PMID: 312863
  170. Immune complex nephritis in Schistosoma mansoni-infected mice.
    Eur J Immunol. 1976 May;6(5):359-64 PMID: 991907
  171. Immune complex detection by immunofluorescence on polymorphonuclear leucocytes.
    Clin Exp Immunol. 1977 Mar;27(3):391-6 PMID: 324668
  172. Letter: Circulating immune complexes in schistosomiasis.
    Br Med J. 1975 May 3;2(5965):274 PMID: 1131583
  173. Autoimmune and polyclonal B cell responses during murine malaria.
    Nature. 1978 Jul 13;274(5667):170-2 PMID: 351426
  174. Comparison of three immunoassays for immune complexes in rheumatoid arthritis.
    Arthritis Rheum. 1979 May;22(5):433-9 PMID: 87203
  175. Detection of immune complex-like materials in cancer patients' sera: a comparative study of results obtained with the C1q deviation and C1q binding tests.
    J Lab Clin Med. 1978 Feb;91(2):191-204 PMID: 413872
  176. Isolation of C1q-binding immune complexes by affinity chromatography and desorption with a diaminoalkyl compound.
    Acta Pathol Microbiol Scand C. 1976 Feb;84(1):45-52 PMID: 773099
  177. The pathogenesis of arthritis associated with acute hepatitis-B surface antigen-positive hepatitis. Complement activation and characterization of circulating immune complexes.
    J Clin Invest. 1975 May;55(5):930-6 PMID: 1123429
  178. Detection of hepatitis B antigen in circulating immune complexes in acute and chronic hepatitis.
    Scand J Immunol. 1977;6(12):1297-304 PMID: 24265
  179. Metabolism of factor B of serum complement in rheumatoid arthritis.
    Clin Exp Immunol. 1978 Oct;34(1):1-9 PMID: 750113
  180. Inhibition of Fc-rosette formation by synovial fluids from patients with rheumatoid arthritis.
    Ann Rheum Dis. 1977 Apr;36(2):170-5 PMID: 857743
  181. Experimental glomerulonephritis. The pathogenesis of a laboratory model resembling the spectrum of human glomerulonephritis.
    J Exp Med. 1961 May 1;113:899-920 PMID: 13723140
  182. Lysis of RNA tumor viruses by human serum: direct antibody-independent triggering of the classical complement pathway.
    J Exp Med. 1976 Oct 1;144(4):970-84 PMID: 62019
  183. Formation and biologic role of polyoma virus-antibody complexes. A critical role for complement.
    J Exp Med. 1974 Aug 1;140(2):549-65 PMID: 4367757
  184. Routine assay for the detection of immune complexes of known immunoglobulin class using solid phase C1q.
    Clin Exp Immunol. 1976 Jun;24(3):396-400 PMID: 939046
  185. Use of circulating immune complex levels in the serodifferentiation of endocarditic and nonendocarditic septicemias.
    Am J Med. 1979 Jan;66(1):58-62 PMID: 420250
  186. Some implications of fatal nephritis associated with mumps.
    Am J Dis Child. 1966 Mar;111(3):297-301 PMID: 5904470
  187. Nephropathy associated with sickle cell anemia: an autologous immune complex nephritis. I. Studies on nature of glomerular-bound antibody and antigen identification in a patient with sickle cell disease and immune deposit glomerulonephritis.
    Am J Med. 1975 Mar;58(3):382-7 PMID: 46705
  188. Evidence that bovine conglutinin reacts with an early product of C3b degradation, and an improved conglutination assay.
    J Immunol. 1978 Aug;121(2):658-64 PMID: 98586
  189. Brief communication: circulating antigen-antibody complex associated with Epstein-Barr virus in recurrent Burkitt's lymphoma.
    J Natl Cancer Inst. 1973 Oct;51(4):1319-21 PMID: 4355608
  190. Circulating immune complexes in pulmonary eosinophilic granuloma.
    Ann Intern Med. 1979 Sep;91(3):397-9 PMID: 382936
  191. Heterogeneity of cold- and warm-reacting cytotoxins against lymphocytes, granulocytes, and monocytes in rheumatic diseases.
    Clin Immunol Immunopathol. 1978 Oct;11(2):142-56 PMID: 737913
  192. Circulating immune complexes in mixed connective tissue disease.
    Arthritis Rheum. 1979 May;22(5):484-9 PMID: 375940
  193. Cryoglobulins in glomerulonephritis not related to systemic disease.
    Kidney Int. 1973 May;3(5):334-41 PMID: 4134520
  194. Intracytoplasmic inclusions of immunoglobulins in rheumatoid arthritis and other diseases.
    Arthritis Rheum. 1968 Apr;11(2):125-34 PMID: 4171444
  195. Bovine antigens and the formation of circulating immune complexes in selective immunoglobulin A deficiency.
    J Clin Invest. 1979 Jul;64(1):272-9 PMID: 571875
  196. Binding of soluble immune complexes to human lymphoblastoid cells. II. Use of Raji cells to detect circulating immune complexes in animal and human sera.
    J Exp Med. 1974 Nov 1;140(5):1230-44 PMID: 4138539
  197. Fc-rosette inhibition by hypocomplementaemic systemic lupus erythematosus sera.
    Ann Rheum Dis. 1975 Oct;35(5):415-21 PMID: 1086653
  198. Renal lesions of subacute infective endocarditis.
    Br Med J. 1974 Apr 6;2(5909):11-4 PMID: 4595180
  199. Differential cytotoxic effect of natural thymocytotoxic autoantibody of NZB mice on functional subsets of T cells.
    J Immunol. 1978 Jun;120(6):1924-9 PMID: 77882
  200. Immune complexes associated with neoplasia: presence of Epstein-Barr virus antigen-antibody complexes in Burkitt's lymphoma.
    Intervirology. 1974;4(5):292-302 PMID: 4377147
  201. Value of immune-complex assays in diagnosis and management.
    Lancet. 1978 Aug 12;2(8085):359-64 PMID: 79721
  202. Reversibility of hepatitis B virus-induced glomerulonephritis and chronic active hepatitis after spontaneous clearance of serum hepatitis B surface antigen.
    Gastroenterology. 1978 Dec;75(6):1152-6 PMID: 710868
  203. Improved detection of immune complexes in human and mouse serum using a microassay adaptation of the C1Q binding test.
    J Immunol Methods. 1979;31(1-2):23-9 PMID: 117056
  204. Immunoglobulin and complement deposition in skin of rheumatoid arthritis and systemic lupus erythematosus patients.
    Ann Rheum Dis. 1976 Aug;35(4):321-6 PMID: 970989
  205. Inhibition of cytotoxicity of nonimmune human lymphocytes for sensitized chicken erythrocytes by aggregated human IgG.
    Scand J Immunol. 1974;3(1):117-25 PMID: 4133398
  206. Immune complexes in cancer: demonstration of complexes in mice bearing neuroblastomas.
    J Natl Cancer Inst. 1975 Jan;54(1):223-8 PMID: 1089793
  207. Detection of circulating antigen-antibody complexes by their inhibitory effect on the agglutination of IgG-coated particles by rheumatioid factor of Clq.
    Clin Exp Immunol. 1976 Aug;25(2):212-26 PMID: 954232
  208. The potential pathogenic role of complement in dengue hemorrhagic shock syndrome.
    N Engl J Med. 1973 Nov 8;289(19):996-1000 PMID: 4742219
  209. Mechanism of binding of soluble immune complexes to lymphocytes.
    Cell Immunol. 1973 Jun;7(3):459-73 PMID: 4541628
  210. The reaction of monomeric and aggregated immunoglobulins with C1.
    Immunochemistry. 1971 Nov;8(11):1011-20 PMID: 4945437
  211. Circulating complement breakdown products in patients with rheumatoid arthritis. Correlation between plasma C3d, circulating immune complexes, and clinical activity.
    J Clin Invest. 1977 May;59(5):862-8 PMID: 853126
  212. Evidence for circulating immune complexes in sarcoidosis.
    Clin Exp Immunol. 1974 Mar;16(3):493-6 PMID: 4468851
  213. Immune complexes and the evolution of Lyme arthritis. Dissemination and localization of abnormal C1q binding activity.
    N Engl J Med. 1979 Dec 20;301(25):1358-63 PMID: 503166
  214. Hepatitis B core antigen immune complexes in the liver of hepatitis B patients.
    Clin Exp Immunol. 1979 Jul;37(1):15-24 PMID: 385186
  215. Immune complexes in cystic fibrosis.
    Br Med J. 1975 Feb 22;1(5955):423-8 PMID: 1090336
  216. Circulating immune complexes in normal human pregnancy.
    Nature. 1977 Apr 7;266(5602):542-3 PMID: 859621
  217. The pathogenesis of arthritis associated with viral hepatitis. Complement-component studies.
    N Engl J Med. 1971 Jul 22;285(4):185-9 PMID: 4996611
  218. Application of the solid phase C1q and Raji cell radioimmune assays for the detection of circulating immune complexes in glomerulonephritis.
    J Clin Invest. 1978 Jul;62(1):61-72 PMID: 659639
  219. Circulating immune complexes in infective endocarditis.
    N Engl J Med. 1976 Dec 30;295(27):1500-5 PMID: 995157
  220. Autosensitization and immune complexes in chronic idiopathic thrombocytopenic purpura.
    Clin Exp Immunol. 1980 Jan;39(1):170-5 PMID: 6993065
  221. Loss of Fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes.
    Nature. 1978 Apr 13;272(5654):618-20 PMID: 306068
  222. Detection of complement activation by counterimmunoelectrophoresis (CIE).
    J Immunol Methods. 1976;13(2):101-12 PMID: 824368
  223. Complement.
    Annu Rev Biochem. 1975;44:697-724 PMID: 1094920
  224. Acute hepatitis: significance of changes in complement components.
    Clin Exp Immunol. 1977 Jun;28(3):496-501 PMID: 891025
  225. Binding of soluble immune complexes to Raji lymphocytes. Role of receptors for complement components, C1q and C3-C3b.
    Immunology. 1978 Apr;34(4):751-61 PMID: 102587
  226. Erythema nodosum leprosum: a clinical manifestation of the arthus phenomenon.
    Lancet. 1969 Nov 1;2(7627):933-5 PMID: 4186599
  227. Immune complexes in human melanoma: a consequence of deranged immune regulation.
    Scand J Immunol. 1976;5(6-7):845-59 PMID: 981971
  228. Some immunological studies of the nephrotic syndrome of Nigerian children.
    Lancet. 1967 Sep 23;2(7517):629-32 PMID: 4166792
  229. IgG antilymphocyte antibodies in SLE detected by 125I protein A.
    Arthritis Rheum. 1976 Nov-Dec;19(6):1261-70 PMID: 1087154
  230. Immune complex systems in the nephritis of systemic lupus erythematosus.
    Kidney Int. 1973 Feb;3(2):90-9 PMID: 4121101
  231. Immune complex disease in experimental animals and man.
    Adv Immunol. 1973;16(0):185-264 PMID: 4599389
  232. Cryoglobulinaemia in tropical splenomegaly syndrome.
    Clin Exp Immunol. 1973 Sep;15(1):65-78 PMID: 4203128
  233. Detection of immune complexes. The use of radioimmunoassays with Clq and monoclonal rheumatoid factor.
    J Clin Invest. 1977 May;59(5):990-1001 PMID: 323292
  234. Virus-like antigen, antibody, and antigen-antibody complexes in hepatitis measured by complement fixation.
    Science. 1969 Jul 18;165(3890):304-6 PMID: 4306916
  235. The affinity of soluble immune complexes for concanavalin A.
    Scand J Immunol. 1978 Apr;7(4):315-20 PMID: 653321
  236. Circulating immune complexes in experimental streptococcal endocarditis: a monitor of therapeutic efficacy.
    J Infect Dis. 1979 Jan;139(1):1-8 PMID: 438528
  237. Immunoglobulin phagocytosis by granulocytes from sera and synovial fluids in various rheumatoid and nonrheumatoid diseases.
    Ann Rheum Dis. 1975 Apr;34(2):146-55 PMID: 806270
  238. Immune complexes in pregnancy.
    Lancet. 1978 Nov 18;2(8099):1108 PMID: 82134
  239. The L1210 radioimmune assay for detecting circulating immune complexes.
    Immunol Commun. 1978;7(5):543-55 PMID: 700778
  240. C1q binding substances in pemphigus and bullous pemphigoid. Detection with a [131I] C1q binding assay.
    Clin Exp Immunol. 1977 Apr;28(1):40-8 PMID: 324678
  241. Metabolism of the third component of complement (C3) in patients with rheumatoid arthritis.
    Arthritis Rheum. 1972 Jan-Feb;15(1):49-56 PMID: 5059642
  242. Association between polyarteritis and Australia antigen.
    Lancet. 1970 Dec 5;2(7684):1149-53 PMID: 4098431
  243. Nature of cold-reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus.
    Arthritis Rheum. 1975 Jan-Feb;18(1):1-8 PMID: 46753
  244. Immunoglobulin in clinically uninvolved skin in systemic lupus erythematosus: association with renal disease.
    J Clin Invest. 1974 May;53(5):1434-40 PMID: 4596508
  245. Cardiopulmonary manifestations of progressive systemic sclerosis: associations with circulating immune complexes and fluorescent antinuclear antibodies.
    Arthritis Rheum. 1979 May;22(5):518-23 PMID: 375941
  246. Evidence for complement-binding immune complexes in adult coeliac disease, Crohn's disease, and ulcerative colitis.
    Lancet. 1973 Feb 24;1(7800):402-3 PMID: 4119709
  247. Application of human erythrocytes to a radioimmune assay of immune complexes in serum.
    Immunology. 1979 Jul;37(3):681-8 PMID: 91576
  248. Inhibition of IgG complex-induced platelet aggregation by antiglobulin-active cryoglobulin IgM components.
    Clin Exp Immunol. 1973 Nov;15(3):393-408 PMID: 4202950
  249. Circulating and intra-articular immune complexes in patients with rheumatoid arthritis. Correlation of 125I-Clq binding activity with clinical and biological features of the disease.
    J Clin Invest. 1976 May;57(5):1308-19 PMID: 944196
  250. Chronic serous otitis media: an immune complex disease.
    Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol. 1977 Mar-Apr;84(2):234-8 PMID: 143103
  251. The nephrotic syndrome associated with secondary syphilis. An immune deposit disease.
    Am J Med. 1970 May;48(5):643-8 PMID: 4912935
  252. Milk precipitins, circulating immune complexes, and IgA deficiency.
    Proc Natl Acad Sci U S A. 1978 Jul;75(7):3387-9 PMID: 277938
  253. Antibody-dependent eosinophil-mediated damage to 51Cr-labeled schistosomula of Schistosoma mansoni: mediation by IgG, and inhibition by antigen-antibody complexes.
    J Immunol. 1977 Jun;118(6):2230-6 PMID: 405426
  254. Multiple immune complexes and hypocomplementaemia in dermatitis herpetiformis and coeliac disease.
    Lancet. 1976 Sep 4;1(7984):487-90 PMID: 74460
  255. The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases.
    J Clin Invest. 1973 Jan;52(1):198-204 PMID: 4629907
  256. The nature and incidence of cryoproteins in hepatitis B antigen (HbsAg) positive patients.
    Q J Med. 1976 Jan;45(177):23-38 PMID: 130650
  257. Serum immune complexes and disease activity in lupus nephritis.
    Lancet. 1977 Mar 12;1(8011):564-7 PMID: 65659
  258. Dissociation of antibody from erythrocyte surfaces by chaotropic ions.
    J Immunol. 1971 Mar;106(3):673-80 PMID: 4324731
  259. Conglutinin and immunoconglutinins.
    Adv Immunol. 1967;6:479-527 PMID: 4860249
  260. Circulating immune complexes in dermatitis herpetiformis.
    Lancet. 1973 Feb 24;1(7800):400-2 PMID: 4119708
  261. Co-occurrence of hepatitis B surface antigen of a particular subtype and antibody to a heterologous subtypic specificity in the same serum.
    J Immunol. 1976 Dec;117(6):2258-9 PMID: 993598
  262. Concurrently circulating hepatitis B surface antigen and heterotypic anti-HBs antibody.
    J Immunol. 1976 Dec;117(6):2262-4 PMID: 993600
  263. Circulating immune complexes after renal transplantation. Correlation of increased 125I-Clq binding activity with acute rejection characterized by fibrin deposition in the kidney.
    J Clin Invest. 1977 Sep;60(3):611-9 PMID: 330564
  264. A solid-phase radioimmunoassay for C1q-binding immune complexes. I. Delta IgG as indicator molecule.
    Scand J Immunol. 1975;4(7):687-97 PMID: 1198070
  265. Immune complexes in peripheral blood polymorphonuclear leucocytes of malignant melanoma patients.
    Clin Exp Immunol. 1978 Jun;32(3):387-91 PMID: 688694
  266. Detection of circulating immune complexes in patients with glomerulonephritis.
    Kidney Int. 1977 Oct;12(4):268-78 PMID: 340763
  267. The choroid plexus in systemic lupus erythematosus.
    Ann Intern Med. 1972 Jan;76(1):65-72 PMID: 4553744
  268. Specific concentration of polynucleotide immune complexes in the cryoprecipitates of patients with systemic lupus erythematosus.
    J Clin Invest. 1975 Sep;56(3):563-70 PMID: 1080489
  269. DNA:anti-DNA complexes: their detection in systemic lupus erythematosus sera.
    J Clin Invest. 1973 Apr;52(4):789-95 PMID: 4693646
  270. Fc-receptors for IgG and IgM immunoglobulins on human T lymphocytes: mode of re-expression after proteolysis or interaction with immune complexes.
    J Immunol. 1978 Aug;121(2):767-70 PMID: 308080
  271. Systemic sclerosis and cryoglobulinemia.
    Clin Immunol Immunopathol. 1976 Jul;6(1):77-82 PMID: 1084824
  272. Polynucleotide immune complexes in serum and glomeruli of patients with systemic lupus erythematosus.
    Am J Pathol. 1974 Jan;74(1):109-24 PMID: 4809310
  273. Detection of immune complexes in serum of patients with ankylosing spondylitis.
    Ann Rheum Dis. 1978 Apr;37(2):159-63 PMID: 646467
  274. Clq: rapid purification method for preparation of monospecific antisera and for biochemical studies.
    J Immunol. 1971 Feb;106(2):304-13 PMID: 5545135
  275. Conglutinin binding polyethylene glycol precipitation assay for immune complexes.
    Clin Exp Immunol. 1979 Nov;38(2):274-83 PMID: 118838
  276. Demonstration of circulating immune complexes in Sjögren's syndrome.
    J Immunol. 1979 Sep;123(3):1382-7 PMID: 469255
  277. Immunoglobulin classes and complement in biopsies of Nigerian children with the nephrotic syndrome.
    Clin Exp Immunol. 1971 May;8(5):761-74 PMID: 4103296
  278. Polymorphonuclear leukocyte inclusions and impaired bacterial killing in patients with Felty's syndrome.
    J Lab Clin Med. 1976 Aug;88(2):183-93 PMID: 182887
  279. The role of the host immune response in the development of tissue lesions associated with African trypanosomiasis in mice.
    Clin Exp Immunol. 1978 Jul;33(1):12-24 PMID: 309369
  280. The pathogenesis of the renal lesion in a patient with streptococcal disease, infected ventriculoatrial shunt, cryogobulinemia and nephritis.
    Am J Med. 1971 Feb;50(2):262-8 PMID: 4100500
  281. The glomerulonephritis of infectious mononucleosis.
    Tex Rep Biol Med. 1968 Winter;26(4):603-12 PMID: 5718721
  282. The Raji cell radioimmune assay for detecting immune complexes in human sera.
    J Clin Invest. 1976 Jan;57(1):169-82 PMID: 128562
  283. Glomerular changes in acute plasmodium falciparum infection. An immunopathologic study.
    Arch Pathol. 1973 Nov;96(5):289-93 PMID: 4200428
  284. Etiology and pathogenesis of a spontaneous lupus-like syndrome in mice.
    Arthritis Rheum. 1978 Jun;21(5 Suppl):S64-7 PMID: 307393
  285. Circulating immune complexes in the serum in systemic lupus erythematosus and in carriers of hepatitis B antigen. Quantitation by binding to radiolabeled C1q.
    J Clin Invest. 1974 Aug;54(2):297-309 PMID: 4847246
  286. Circulating immune complexes in various thyroid diseases.
    Clin Exp Immunol. 1979 Jun;36(3):379-83 PMID: 487642
  287. An unusual protein component of high molecular weight in the serum of certain patients with rheumatoid arthritis.
    J Exp Med. 1957 May 1;105(5):425-38 PMID: 13428913
  288. Complement bridges between cells analysis of a possible cell-cell interaction mechanism.
    J Exp Med. 1977 Dec 1;146(6):1484-99 PMID: 925610
  289. An approach to the routine estimation of circulating carcinoembryonic antigen immune complexes in patients with carcinomata of the gastrointestinal tract.
    Clin Exp Immunol. 1979 Jul;37(1):25-32 PMID: 226300
  290. Circulating immune complexes in sera of patients with Burkett's lymphoma and nasopharyngeal carcinoma.
    Int J Cancer. 1976 Sep 15;18(3):310-6 PMID: 783053
  291. Circulating immune complexes after kidney transplantation.
    Transplantation. 1976 APR;21(4):312-6 PMID: 781932
  292. Free "small" and IgG-associated "large" hepatitis B e antigen in the serum and glomerular capillary walls of two patients with membranous glomerulonephritis.
    N Engl J Med. 1979 Apr 12;300(15):814-9 PMID: 370592
  293. Immune function in ankylosing spondylitics and their relatives: influence of disease and HLA B27.
    Clin Exp Immunol. 1978 Aug;33(2):270-5 PMID: 102477
  294. The mechanism of action of the C3b inactivator (conglutinogen-activating factor) on its naturally occurring substrate, the major fragment of the third component of complement (C3b).
    J Exp Med. 1975 May 1;141(5):1221-6 PMID: 1168693
  295. Immune monitoring protocol for patients with carcinoma of the head and neck. Preliminary report.
    Ann Otol Rhinol Laryngol. 1978 Sep-Oct;87(5 Pt 1):692-700 PMID: 309748
  296. Soluble immune complexes in sera of patients with nephritis.
    Kidney Int. 1976 Sep;10(3):256-63 PMID: 135115
  297. Hepatitis associated antigen and periarteritis nodosa (PAN).
    Vox Sang. 1970 Sep-Oct;19(3):410-1 PMID: 4396040
  298. Isolation of soluble immune complexes by affinity chromatography using staphylococcal protein A--Sepharose as substrate.
    J Immunol Methods. 1977;18(1-2):183-92 PMID: 915308
  299. Immunopathogenesis of syphilitic glomerulonephritis. Elution of antitreponemal antibody from glomerular immune-complex deposits.
    N Engl J Med. 1975 Feb 27;292(9):449-54 PMID: 1089888
  300. Renal changes in patients with hepatosplenic schistosomiasis.
    Am J Trop Med Hyg. 1971 Jan;20(1):77-83 PMID: 5567743
  301. Binding of soluble immune complexes to human lymphoblastoid cells. I. Characterization of receptors for IgG Fc and complement and description of the binding mechanism.
    J Exp Med. 1974 Oct 1;140(4):877-94 PMID: 4139225
  302. Solid-phase enzyme immunoassay or radioimmunoassay for the detection of immune complexes based on their recognition by conglutinin: conglutinin-binding test. A comparative study with 125I-labelled Clq binding and Raji-cell RIA tests.
    Clin Exp Immunol. 1977 Aug;29(2):342-54 PMID: 332422
  303. NIH conference. Primary biliary cirrhosis and the complement system.
    Ann Intern Med. 1979 Jan;90(1):72-84 PMID: 420467
  304. Formation of leukocyte inclusions in normal polymorphonuclear cells incubated with synovial fluid.
    Arthritis Rheum. 1970 Nov-Dec;13(6):724-33 PMID: 4992982
  305. Effect of chemical and enzymatic radioiodination on in vitro human Clq activities.
    J Immunol. 1973 Mar;110(3):820-8 PMID: 4734666
  306. Gamma globulin complexes in rheumatoid arthritis and certain other conditions.
    J Clin Invest. 1961 Jan;40:117-29 PMID: 13755149
  307. Cryoglobulins. III. Further studies on the nature, incidence, clinical, diagnostic, prognostic, and immunopathologic significance of cryoproteins in renal disease.
    Q J Med. 1975 Apr;44(174):285-307 PMID: 1101284
  308. Relationship between anti-DNA antibodies complement consumption and circulating immune complexes in systemic lupus erythematosus.
    Clin Exp Immunol. 1977 May;28(2):226-32 PMID: 301447
  309. Detection of immune complexes: techniques and implications.
    Hosp Pract. 1980 May;15(5):107-11, 114-7, 121 PMID: 6989743
  310. Arthritis associated with intestinal-bypass procedure for morbid obesity. Complement activation and characterization of circulating cryoproteins.
    N Engl J Med. 1976 Jan 15;294(3):121-4 PMID: 1105187
  311. Quantitative elution studies in experimental immune complex and nephrotoxic nephritis.
    Clin Exp Immunol. 1977 Aug;29(2):334-41 PMID: 20255
  312. The composition of pulmonary immune deposits in systemic lupus erythematosus.
    Clin Immunol Immunopathol. 1979 Feb;12(2):204-19 PMID: 369753
  313. Evidence for the presence of receptors for C3 and IgG Fc on human synovial cells.
    Arthritis Rheum. 1980 Jan;23(1):1-9 PMID: 7352929
  314. The glomerulopathy of congenital syphilis--an immune deposit disease.
    J Pediatr. 1972 Dec;81(6):1154-6 PMID: 4566039
  315. Complement levels in acute infectious hepatitis and serum hepatitis.
    Clin Exp Immunol. 1972 May;11(1):31-5 PMID: 4624985
  316. Human lymphocytes bear membrane receptors for C3b and C3d.
    J Clin Invest. 1973 Dec;52(12):3239-42 PMID: 4543024
  317. Binding and activation of the first component of human complement by the lipid A region of lipopolysaccharides.
    J Immunol. 1978 Jun;120(6):1862-8 PMID: 351060
  318. Classification of leprosy according to immunity. A five-group system.
    Int J Lepr Other Mycobact Dis. 1966 Jul-Sep;34(3):255-73 PMID: 5950347
  319. The binding of murine immunoglobulins to staphylococcal protein A.
    J Immunol. 1978 May;120(5):1493-6 PMID: 659858
  320. Evidence for immune-complex formation in patients with amyotrophic lateral sclerosis.
    Lancet. 1976 Jul 24;2(7978):169-72 PMID: 73795
  321. Circulating immune complexes and monocyte Fc function in autoimmune diseases.
    Ann Rheum Dis. 1979 Feb;38(1):79-83 PMID: 434951
  322. "Protein A" from S. aureus. I. Pseudo-immune reaction with human gamma-globulin.
    J Immunol. 1966 Dec;97(6):822-7 PMID: 4163007
  323. Circulating immune complexes in ulcerative colitis. I. Correlation to disease activity.
    Clin Exp Immunol. 1978 Jan;31(1):72-80 PMID: 346271
  324. Cryoglobulinaemia and circulating immune complexes in tropical splenomegaly syndrome.
    Clin Exp Immunol. 1978 Jan;31(1):55-8 PMID: 639349
  325. Immune complexes in hepatitis B antigen-associated periarteritis nodosa. Detection by antibody-dependent cell-mediated cytotoxicity and the Raji cell assay.
    Am J Med. 1977 May;62(5):783-91 PMID: 16490
  326. A radioimmunoassay for human antigen-antibody complexes in clinical material.
    J Immunol. 1975 Jan;114(1 Pt 1):5-9 PMID: 1167561
  327. IMMUNOCHEMICAL STUDIES ON RABBIT ANTI-ANTIBODY.
    J Immunol. 1964 Feb;92:227-33 PMID: 14160443
  328. A comparative histologic and immunologic study in rabbits of induced hypersensitivity of the serum sickness type.
    J Exp Med. 1953 Feb 1;97(2):257-82 PMID: 13022878
  329. Circulating immune complexes in retinal vasculitis.
    Clin Exp Immunol. 1977 Jul;29(1):23-9 PMID: 891035
  330. Detection of circulating immune complexes in human sera by simplified assays with polyethylene glycol.
    J Immunol Methods. 1977;16(2):165-83 PMID: 881555
  331. Diffuse glomerulonephritis associated with infected ventriculoatrial shunt.
    N Engl J Med. 1968 Nov 14;279(20):1077-82 PMID: 4176718
  332. Isolation of soluble immune complexes from serum using protein A bearing Staphylococcus aureus bacteria: separation of the antigen from immune complex and production of antisera.
    Clin Immunol Immunopathol. 1980 Jan;15(1):76-87 PMID: 6153587
  333. Comparison of the presence of immune complexes in Felty's syndrome and rheumatoid arthritis.
    Arthritis Rheum. 1978 Apr;21(3):310-5 PMID: 417729
  334. Detection of IgG aggregates or immune complexes using solid-phase C1q and protein A-rich Staphylococcus aureus as an indicator system.
    Scand J Immunol. 1975;4(7):673-80 PMID: 1198069
  335. Circulating soluble immume complexes in recurrent oral ulceration and Behçet's syndrome.
    Clin Exp Immunol. 1978 May;32(2):193-8 PMID: 668196
  336. Isolation of circulating immune complexes using Raji cells. Separation of antigens from immune complexes and production of antiserum.
    J Clin Invest. 1978 Jun;61(6):1570-81 PMID: 659616
  337. Circulating DNA:anti-DNA complexes in systemic lupus erythematosus. Detection and characterization by ultracentrifugation.
    J Clin Invest. 1979 Jul;64(1):191-8 PMID: 36410
  338. Deposition of IgM and complement at the dermoepidermal junction in acute and chronic cutaneous graft-vs-host disease in man.
    J Immunol. 1978 May;120(5):1485-92 PMID: 26718
  339. Case of glomerulonephritis associated with acute toxoplasmosis.
    Br Med J. 1974 Sep 14;3(5932):664-5 PMID: 4279124
  340. Enhanced uptake by guinea-pig macrophages of radio-iodinated human aggregated immunoglobulin G in the presence of sera from rheumatoid patients with cutaneous vasculitis.
    Clin Exp Immunol. 1975 Feb;19(2):267-80 PMID: 1082388
  341. Metabolism of autologous and homologous IgG in rheumatoid arthritis.
    J Clin Invest. 1977 Aug;60(2):313-22 PMID: 874093
  342. Serum and blister fluid anticomplementary activity in pemphigus and bullous pemphigoid. Sucrose density gradient studies.
    Proc Soc Exp Biol Med. 1976 Mar;151(3):594-8 PMID: 768993
  343. Circulating immune complexes in cutaneous vasculitis. Detection with C1q and monoclonal rheumatoid factor.
    J Clin Invest. 1979 Dec;64(6):1652-60 PMID: 500831
  344. Characterization of IgG complexes in patients with rheumatoid arthritis.
    Ann N Y Acad Sci. 1975 Jun 13;256:73-81 PMID: 808994
  345. Circulating immune complexes and complement activation in primary biliary cirrhosis.
    N Engl J Med. 1978 Feb 2;298(5):233-7 PMID: 619265
  346. Circulating antigens and immune complexes in Schistosoma mansoni-infected rats. Characterization by radioimmunoprecipitation-PEG assay (RIPEGA).
    Clin Exp Immunol. 1978 Jun;32(3):435-42 PMID: 688695
  347. Immune complex nephropathy i schistosomiasis.
    Ann Intern Med. 1975 Aug;83(2):148-54 PMID: 125058
  348. The nephrotic syndrome in congenital syphilis: an immunopathy.
    Pediatrics. 1972 Feb;49(2):260-6 PMID: 4551017
  349. Rheumatoid factors reacting with autologous native gamma-G-globulin and joint fluid gamma-G aggregates.
    Clin Exp Immunol. 1968 Sep;3(7):671-90 PMID: 4973612
  350. Occurrence of -globulin complexes in serum and joint fluid of rheumatoid arthritis patients: use of monoclonal rheumatoid factors as reagents for their demonstration.
    J Exp Med. 1971 Sep 1;134(3 Pt 2):286s-295s PMID: 4998932
  351. Expression and function of idiotypes of lymphocytes.
    Adv Immunol. 1978;26:195-254 PMID: 80953
  352. Inhibition of antibody-dependent cell-mediated cytotoxicity (ADCC) as a means of detection of immune complexes in the sera of patients with thyroid disorders and bronchogenic carcinoma.
    Clin Exp Immunol. 1976 Aug;25(2):270-9 PMID: 986262
  353. Rabbit C1q: purification, functional and structural studies.
    J Immunol Methods. 1972 Nov;2(1):25-34 PMID: 4139208
  354. The immune nature of subacute bacterial endocarditis (SBE) nephritis.
    Am J Med. 1973 May;54(5):645-52 PMID: 4121911
  355. Studies on the biological properties of antigen-antibody complexes. I. Anaphylatic shock induced by soluble antigen-antibody complexes in unsensitized normal guinea pigs.
    Bull Johns Hopkins Hosp. 1957 Jul;101(1):13-44 PMID: 13436933
  356. The occurrence of circulating immune complexes and viral antigens in idiopathic thrombocytopenic purpura.
    Clin Exp Immunol. 1977 Apr;28(1):49-55 PMID: 558848
  357. Complement metabolism in rheumatoid arthritis. I. Longitudinal studies.
    Ann Rheum Dis. 1973 Nov;32(6):557-64 PMID: 4148547
  358. Experimental glomerulonephritis: immunological events and pathogenetic mechanisms.
    Adv Immunol. 1967;6:1-90 PMID: 4860246
  359. Longitudinal study of circulating immune complexes in a patient with Staphylococcus albus-induced shunt nephritis.
    Clin Exp Immunol. 1979 Aug;37(2):228-38 PMID: 115626
  360. Circulating immune complexes in a patient with meningococcal disease.
    Br Med J. 1976 Jun 12;1(6023):1445-6 PMID: 953534
  361. Biological activities of immunoglobulins of different classes and subclasses.
    Adv Immunol. 1974;19(0):259-94 PMID: 4611173
  362. Lymphocytes transformed by Epstein-Barr virus. Induction of nuclear antigen reactive with antibody in rheumatoid arthritis.
    J Exp Med. 1978 Apr 1;147(4):1018-27 PMID: 206643
  363. Direct evidence for circulating DNA/anti-DNA complexes in systemic lupus erythematosus.
    Arthritis Rheum. 1978 Jan-Feb;21(1):17-22 PMID: 623690
  364. Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody.
    J Exp Med. 1977 Jul 1;146(1):201-17 PMID: 406347
  365. A test for antigen--antibody complexes in human sera using IgM of rabbit antisera to human immunoglobulins.
    Clin Exp Immunol. 1977 Sep;29(3):428-35 PMID: 589862
  366. Immune-complex assays: the state of the art.
    N Engl J Med. 1978 Jan 19;298(3):161-2 PMID: 145542
  367. Precipitin reactions of the C1q component of complement with aggregated gamma-globulin and immune complexes in gel diffusion.
    Immunology. 1970 Dec;19(6):909-19 PMID: 4098878
  368. Detection of antibodies and soluble antigen-antibody complexes by precipitation with polyethylene glycol.
    J Immunol. 1973 Oct;111(4):1219-27 PMID: 4728683
  369. In vitro immune responsiveness to vaccinea virus and HLA.
    N Engl J Med. 1977 Sep 29;297(13):692-6 PMID: 70749
  370. Factors relating to circulating immune complexes in rheumatoid arthirits.
    Ann Rheum Dis. 1976 Aug;35(4):314-20 PMID: 970988
  371. Changes of Fcgamma receptor-related properties induced by interaction of human lymphocytes with insoluble immune complexes.
    J Immunol. 1977 Dec;119(6):1943-8 PMID: 562379
  372. Extracellular release of peroxidase from eosinophils by interaction with immune complexes.
    Clin Exp Immunol. 1977 Apr;28(1):56-60 PMID: 301076
  373. Immune complexes in ulcerative colitis and Crohn's disease.
    Clin Exp Immunol. 1977 Aug;29(2):187-96 PMID: 908171
  374. Antigen-antibody complexes elicit anti-idiotypic antibodies to self-idiotopes.
    Nature. 1978 Mar 16;272(5650):265-6 PMID: 305008
  375. Immune complexes in hepatitis.
    Lancet. 1969 Nov 8;2(7628):983-6 PMID: 4186979
  376. Reactions of staphylococcal antigens with normal sera, gamma G-globulins, and gamma G-globulin fragments of various species origin.
    Acta Pathol Microbiol Scand B Microbiol Immunol. 1970;78(1):106-11 PMID: 4192776
  377. Immune complexes and complement hypercatabolism in patients with leprosy.
    Clin Exp Immunol. 1976 Dec;26(3):388-96 PMID: 1009681
  378. Phagocytosis of immune complexes by polymorphonuclear leucocytes in patients with Felty's syndrome.
    Clin Exp Immunol. 1977 Jun;28(3):413-25 PMID: 196798
  379. Cryoglobulinaemia in human renal diseases. A study of seventy-six cases.
    Clin Exp Immunol. 1973 Dec;15(4):483-96 PMID: 4778718
  380. CONGLUTINATION: SPECIFIC INHIBITION BY CARBOHYDRATES.
    Science. 1964 Mar 20;143(3612):1327-8 PMID: 14113618
  381. Clinical correlates of C1Q-precipitating substances in the sera of patients with leprosy.
    Am J Trop Med Hyg. 1974 May;23(3):471-5 PMID: 4823798
  382. Vasculitis in association with Australia antigen.
    J Exp Med. 1971 Sep 1;134(3 Pt 2):330s-336s PMID: 4398321
  383. STUDIES ON THE DEPRESSED HEMOLYTIC COMPLEMENT ACTIVITY OF SYNOVIAL FLUID IN ADULT RHEUMATOID ARTHRITIS.
    Acta Rheumatol Scand. 1963;9:165-93 PMID: 14088651
  384. Reduction of immune complexes and immunoglobulins induced by D-penicillamine in primary biliary cirrhosis.
    N Engl J Med. 1979 Feb 8;300(6):274-8 PMID: 759879
  385. Complement, lymphocytotoxins and immune complexes in infectious mononucleosis: serial studies in uncomplicated cases.
    Clin Exp Immunol. 1978 Nov;34(2):241-7 PMID: 737909
  386. Arthritis after meningococcal meningitis.
    Br Med J. 1977 Mar 5;1(6061):618 PMID: 139189
  387. Sjögren's syndrome: a defect in reticuloendothelial system Fc-receptor-specific clearance.
    Ann Intern Med. 1979 Oct;91(4):534-8 PMID: 484951
  388. Serial studies on circulating immune complexes in post-streptococcal sequelae.
    Clin Exp Immunol. 1978 Dec;34(3):318-25 PMID: 743806
  389. Tissue localization of Australia antigen immune complexes in acute and chronic hepatitis and liver cirrhosis.
    Am J Pathol. 1972 Jul;68(1):31-56 PMID: 4628111
  390. Specifically cytotoxic lymphocytes produced by preincubation with antibody-complexed target cells.
    J Immunol. 1972 Feb;108(2):558-61 PMID: 5049099
  391. Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus.
    N Engl J Med. 1979 Mar 8;300(10):518-23 PMID: 763252
  392. Immune complex detection and complement activity in rheumatoid arthritis: a comparative study of a radioimmunoassay using monoclonal rheumatoid factor, gel diffusion techniques and C4 activity.
    Clin Exp Immunol. 1978 Nov;34(2):226-34 PMID: 737907
  393. Use of bovine conglutinin for the assay of immune complexes.
    J Immunol. 1977 Apr;118(4):1428-34 PMID: 850071
  394. Circulating immune complexes in systemic lupus erythematosus.
    Clin Exp Immunol. 1977 Aug;29(2):197-204 PMID: 302768
  395. Nephropathy associated with sickle cell anemia: an autologous immune complex nephritis. II. Clinicopathologic study of seven patients.
    Am J Med. 1975 Nov;59(5):650-9 PMID: 128292
  396. Factors interfering with immunological rejection of tumours.
    Br Med Bull. 1976 May;32(2):118-23 PMID: 782631
  397. Congenital nephrotic syndrome associated with congenital toxoplasmosis.
    J Pediatr. 1974 Sep;85(3):366-70 PMID: 4610418
  398. Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies.
    J Clin Invest. 1974 Nov;54(5):1082-92 PMID: 4138924
  399. Relationship of levels of circulating immune complexes to histologic patterns of nephritis: a comparative study of membranous glomerulonephropathy and diffuse proliferative glomerulonephritis.
    J Lab Clin Med. 1977 Nov;90(5):891-8 PMID: 908876
  400. Circulating immune complexes in multiple sclerosis and other neurological diseases.
    Lancet. 1976 Nov 6;2(7993):997-9 PMID: 62267
  401. The nephrotic syndrome secondary to acute glomerulonephritis during falciparum malaria.
    Ann Intern Med. 1967 Dec;67(6):1163-71 PMID: 4863108
  402. Detection and characterization of immune complexes by the platelet aggregation test. I. Complexes formed in vitro.
    Clin Exp Immunol. 1971 Mar;8(3):389-97 PMID: 5576659
  403. Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. I. Relationship of antibody production to disease in neonatally infected mice.
    J Exp Med. 1969 Mar 1;129(3):483-505 PMID: 4179834
  404. Complement and meningococcal infection.
    Br Med J. 1976 Apr 3;1(6013):797-9 PMID: 1260336
  405. The viral envelope glycoprotein of murine leukemia virus and the pathogenesis of immune complex glomerulonephritis of New Zealand mice.
    J Exp Med. 1974 Oct 1;140(4):1011-27 PMID: 4279268
  406. Circulating immune complexes and symptoms in Hodgkin's disease.
    Lancet. 1976 Feb 28;1(7957):449-51 PMID: 55719
  407. Circulating carcinoembryonic antigen immune complexes in sera of patients with carcinomata of the gastrointestinal tract.
    Clin Exp Immunol. 1979 Feb;35(2):190-5 PMID: 108040
  408. Studies of cryoprecipitates from synovial fluid of rheumatoid patients.
    Immunology. 1971 Jun;20(6):1067-77 PMID: 4997575
  409. Circulating immune complexes in the idiopathic interstitial pneumonias.
    N Engl J Med. 1978 Feb 16;298(7):353-7 PMID: 146160
Article Info
Journal
The American journal of pathology
Abbr.
Am J Pathol
ISSN
0002-9440
Published
1980-08-00
Pages
529-94
Language
English
Region
United States
NLM ID
0370502
PMCID
PMC1903541
Subset
IM
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