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PMID: 6308563 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

The complete nucleotide sequence of the rat 18S ribosomal RNA gene and comparison with the respective yeast and frog genes.

Nucleic acids research ·Vol. 11 ·No. 14 ·1983-07-25 ·Pages 4879-90

Torczynski R, Bollon AP, Fuke M

Abstract

The complete nucleotide sequence of the rat 18S ribosomal RNA gene has been determined. A comparison of the rat 18S ribosomal RNA gene sequence with the known sequences of yeast and frog revealed three conserved (stable) regions, two unstable regions, and three large inserts. (A,T) leads to (G,C) changes were more frequent than (G,C) leads to (A,T) changes for three comparisons (yeast leads to frog, frog leads to rat, and yeast leads to rat). GC pairs were inserted preferentially over AT pairs for the same three comparisons. These two factors contribute to the progressively higher GC content of 18S ribosomal RNA of yeast, frog, and rat.

MeSH Terms
Animals Bacteriophage lambda/genetics Base Sequence Cloning, Molecular DNA/genetics DNA Restriction Enzymes DNA Transposable Elements DNA, Ribosomal Genes Molecular Weight Plasmids RNA, Ribosomal/genetics Rats Saccharomyces cerevisiae/genetics Species Specificity Xenopus
Chemicals
DNA Transposable Elements DNA, Ribosomal RNA, Ribosomal DNA DNA Restriction Enzymes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Torczynski R
Bollon A P
Fuke M
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25 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/11.14.4879
Published
1983-07-25
Pages
4879-90
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326092
Subset
IM
Grants
NIGMS NIH HHS · GM-28090 · United States
Databases
GENBANK
M11188
External Links
PubMed source DOI: 10.1093/nar/11.14.4879 PMC Full Text View journal details
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