-
Immunogenicity and efficacy testing in chimpanzees of an oral hepatitis B vaccine based on live recombinant adenovirus.
Proc Natl Acad Sci U S A. 1989 Sep;86(17):6763-7
PMID: 2570422
-
DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines.
Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7213-8
PMID: 8692971
-
Genetic immunization is a simple method for eliciting an immune response.
Nature. 1992 Mar 12;356(6365):152-4
PMID: 1545867
-
Synthesis in animal cells of hepatitis B surface antigen particles carrying a receptor for polymerized human serum albumin.
Proc Natl Acad Sci U S A. 1984 Dec;81(24):7708-12
PMID: 6096851
-
Hepatitis B virus contains pre-S gene-encoded domains.
Nature. 1985 May 9-15;315(6015):154-6
PMID: 2581144
-
Induction of anti-hepatitis B surface antigen (HBsAg) antibodies in HBsAg producing transgenic mice: a possible way of circumventing "nonresponse" to HBsAg.
J Med Virol. 1993 Jan;39(1):67-74
PMID: 7678639
-
DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein.
Hum Gene Ther. 1995 Nov;6(11):1447-56
PMID: 8573617
-
Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle.
Hum Gene Ther. 1993 Dec;4(6):733-40
PMID: 8186288
-
The immune response to hepatitis B vaccine in humans: inheritance patterns in families.
J Exp Med. 1992 Feb 1;175(2):495-502
PMID: 1531063
-
DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state.
Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12496-501
PMID: 8901610
-
Recombinant versus plasma-derived hepatitis B vaccines: issues of safety, immunogenicity and cost-effectiveness.
Vaccine. 1988 Aug;6(4):299-303
PMID: 2973187
-
Neonatal tolerance revisited: turning on newborn T cells with dendritic cells.
Science. 1996 Mar 22;271(5256):1723-6
PMID: 8596932
-
Direct gene transfer into mouse muscle in vivo.
Science. 1990 Mar 23;247(4949 Pt 1):1465-8
PMID: 1690918
-
T- and B-cell recognition of hepatitis B viral antigens.
Immunol Today. 1988 Dec;9(12):380-6
PMID: 3076412
-
Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA.
Gene Ther. 1997 Mar;4(3):181-8
PMID: 9135731
-
Hepatitis B virus antigens made in microbial cells immunise against viral infection.
EMBO J. 1984 Mar;3(3):645-50
PMID: 6370689
-
Update on hepatitis B prevention.
MMWR Morb Mortal Wkly Rep. 1987 Jun 19;36(23):353-60, 366
PMID: 2953959
-
The molecular biology of the hepatitis B viruses.
Annu Rev Biochem. 1987;56:651-93
PMID: 3039907
-
Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen.
Vaccine. 1994 Dec;12(16):1503-9
PMID: 7879414
-
Synthesis and assembly of hepatitis B virus surface antigen particles in yeast.
Nature. 1982 Jul 22;298(5872):347-50
PMID: 7045698
-
Protection against hepatitis B virus infection by immunization with hepatitis B core antigen.
Gastroenterology. 1985 Mar;88(3):763-7
PMID: 3967809
-
Successful nucleic acid based immunization of newborn chimpanzees against hepatitis B virus.
Vaccine. 1997 Jun;15(8):916-9
PMID: 9234547
-
DNA-mediated immunization to hepatitis B surface antigen: longevity of primary response and effect of boost.
Vaccine. 1996 Jun;14(9):910-5
PMID: 8843634
-
Live recombinant vaccinia virus protects chimpanzees against hepatitis B.
Nature. 1984 Sep 6-11;311(5981):67-9
PMID: 6472464
-
Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice.
Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3764-8
PMID: 8170985
-
DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.
Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5307-11
PMID: 7777503
-
DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody.
Hum Mol Genet. 1993 Nov;2(11):1847-51
PMID: 8281146
-
Immunostimulatory DNA sequences necessary for effective intradermal gene immunization.
Science. 1996 Jul 19;273(5273):352-4
PMID: 8662521
-
Hepatitis B subunit vaccine: a preliminary report of safety and efficacy tests in chimpanzees.
Am J Med Sci. 1975 Sep-Oct;270(2):395-9
PMID: 828832
-
Development and chimpanzee testing of a vaccine against human hepatitis B.
Proc Soc Exp Biol Med. 1976 Apr;151(4):694-700
PMID: 817293
-
A synthetic peptide vaccine involving the product of the pre-S(2) region of hepatitis B virus DNA: protective efficacy in chimpanzees.
Proc Natl Acad Sci U S A. 1986 Dec;83(23):9174-8
PMID: 3466181
-
Immunization with soluble hepatitis B virus surface protein elicits murine H-2 class I-restricted CD8+ cytotoxic T lymphocyte responses in vivo.
J Immunol. 1994 Feb 1;152(3):1110-9
PMID: 8301120
-
Specific expression of hepatitis B surface antigen (HBsAg) in transgenic mice.
Science. 1985 Dec 6;230(4730):1160-3
PMID: 3865370
-
Immunisation against hepatitis B in man.
Lancet. 1976 Jun 26;1(7974):1367-70
PMID: 59012
-
Hepatitis B vaccine passes first major test.
Science. 1980 Nov 14;210(4471):760-2
PMID: 6254146
-
Antibodies to a synthetic peptide from the preS 120-145 region of the hepatitis B virus envelope are virus neutralizing.
Vaccine. 1986 Mar;4(1):35-7
PMID: 2421497
-
Antibody response to pre-S2 and hepatitis B virus induced liver damage.
Lancet. 1988 Jun 25;1(8600):1421-4
PMID: 2898582
-
CpG motifs in bacterial DNA trigger direct B-cell activation.
Nature. 1995 Apr 6;374(6522):546-9
PMID: 7700380