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PMID: 6370689 Published · ppublish English Journal Article

Hepatitis B virus antigens made in microbial cells immunise against viral infection.

The EMBO journal ·Vol. 3 ·No. 3 ·1984-03-00 ·Pages 645-50

Murray K, Bruce SA, Hinnen A, Wingfield P, van Erd PM, de Reus A, Schellekens H

Abstract

Chimpanzees have been vaccinated successfully against hepatitis B virus with preparations of the viral antigens made in microbial cells by genetic engineering methods.

MeSH Terms
Animals Cloning, Molecular Escherichia coli/genetics Female Hepatitis B/prevention & control Hepatitis B Antigens/genetics,immunology Immunization Male Pan troglodytes Saccharomyces cerevisiae/genetics Viral Vaccines/immunology
Chemicals
Hepatitis B Antigens Viral Vaccines
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Murray K
Bruce S A
Hinnen A
Wingfield P
van Erd P M
de Reus A
Schellekens H
References (34)
34 references, click to expand
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Article Info
Journal
The EMBO journal
Abbr.
EMBO J
ISSN
0261-4189
Published
1984-03-00
Pages
645-50
Language
English
Region
England
NLM ID
8208664
PMCID
PMC557401
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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