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RARA haploinsufficiency modestly influences the phenotype of APL

Samples:10 Organism:Mus musculus Type:transcription profiling by array July 29, 2010

...RARA+/- mice with mice expressing PML-RARA from the Cathepsin G locus (mCG-PR). We found that RARA haploinsufficiency co...

Transcription profiling by array of K. pneumoniae to investigate the regulon of…

Samples:6 Organism:Klebsiella pneumoniae Type:transcription profiling by array March 21, 2013

...RarA. This was done by comparing the transcriptome profiles between a rarA overexpressor and the baseline control. RarA ...

Transcription profiling of human U937T:PLZF-RARa Inducible Cells

Samples:6 Organism:Homo sapiens Type:transcription profiling by array Dec. 5, 2009

...RARa cell line was engineered to express PLZF-RARa upon tetracycline removal. PLZF-RARa was induced for 48hr and RNA was...

Expression and function of PML-RARA in the multipotent hematopoietic progenitor…

Samples:69 Organism:Mus musculus Type:transcription profiling by array Aug. 13, 2012

...RARA targeted to the Ctsg locus (in Ctsg-PML-RARA mice) are detected in the purified KLS cells of these mice (Kit+Lin-Sc...

Negative regulation of the IFN/STAT signaling pathway by the Trim24 tumor suppr…

Samples:22 Organism:Mus musculus Type:transcription profiling by array Aug. 1, 2011

...Rara)-dependent transcription and cell proliferation. However, it is unknown which downstream targets of Rara regulated ...

mCG-PML-RARA alters multipotent hematopoiesis

Samples:13 Organism:Mus musculus Type:transcription profiling by array Oct. 21, 2010

...RARA expression and late myeloid maturation arrest. The myeloid restriction of PML-RARA dependent leukemia has been reca...

Effect of PML/RARA on the transcriptome of preleukemic early promyelocytes vs P…

Samples:8 Organism:Mus musculus Type:transcription profiling by array July 15, 2015

...RARA at the early promyelocyte stage (4 weeks old, preleukemic) and in full blown PML/RARA leukemia generated by transdu...

DNA methylation changes are a late event in Acute Promyelocytic Leukemia and co…

Samples:51 Organism:Homo sapiens, Mus musculus Type:ChIP-seq, methylation profiling by high… Nov. 8, 2012

...RARa knock-in mice did not show altered DNA methylation and expression of PML-RARa in hematopoietic progenitor cells pre...

Effect of PML/RARa on the transcriptome of maturing myeloid populations in vivo

Samples:20 Organism:Mus musculus Type:transcription profiling by array June 24, 2015

...RARa transgenics after 2 rounds of sorting. Two-conditions experiment: Wt vs PML/RARa. 3 populations: GMP, Early Pros, L...

Maintenance of Leukemic Cell Identity by the Activity of the Polycomb Complex P…

Samples:5 Organism:Mus musculus Type:ChIP-seq Oct. 21, 2016

...RARa. Immuno-precipitation of formaldehyde cross-linked chromatin prepared from Cdkn2a-/- Lin- HSC cells non-transduced ...

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