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PMID: 19478073 Published · ppublish English Journal Article Review

Functional analysis of transcription factors in Arabidopsis.

Plant & cell physiology ·Vol. 50 ·No. 7 ·2009-07-00 ·Pages 1232-48

Mitsuda N, Ohme-Takagi M

Abstract

Transcription factors (TFs) regulate the expression of genes at the transcriptional level. Modification of TF activity dynamically alters the transcriptome, which leads to metabolic and phenotypic changes. Thus, functional analysis of TFs using 'omics-based' methodologies is one of the most important areas of the post-genome era. In this mini-review, we present an overview of Arabidopsis TFs and introduce strategies for the functional analysis of plant TFs, which include both traditional and recently developed technologies. These strategies can be assigned to five categories: bioinformatic analysis; analysis of molecular function; expression analysis; phenotype analysis; and network analysis for the description of entire transcriptional regulatory networks.

MeSH Terms
Arabidopsis/genetics,metabolism Arabidopsis Proteins/genetics,metabolism Computational Biology Databases, Genetic Gene Expression Profiling Gene Expression Regulation, Plant Gene Regulatory Networks Phenotype RNA, Plant/genetics Transcription Factors/genetics,metabolism
Chemicals
Arabidopsis Proteins RNA, Plant Transcription Factors
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Mitsuda Nobutaka
Research Institute of Genome-Based Biofactory, National Institute of Advanced Industrial Science and Technology (AIST), Central 4, Higashi, Tsukuba, Japan.
Ohme-Takagi Masaru
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Article Info
Journal
Plant & cell physiology
Abbr.
Plant Cell Physiol
ISSN
1471-9053
DOI
10.1093/pcp/pcp075
Published
2009-07-00
Epub
2009-00-28
Pages
1232-48
Language
English
Region
Japan
NLM ID
9430925
PMCID
PMC2709548
Subset
IM
External Links
PubMed source DOI: 10.1093/pcp/pcp075 PMC Full Text View journal details
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