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PMID: 24093022 Published · epublish English Journal Article Review

Evolution and Conservation of Plant NLR Functions.

Frontiers in immunology ·Vol. 4 ·2013-09-25 ·Pages 297

Jacob F, Vernaldi S, Maekawa T

Abstract

In plants and animals, nucleotide-binding domain and leucine-rich repeats (NLR)-containing proteins play pivotal roles in innate immunity. Despite their similar biological functions and protein architecture, comparative genome-wide analyses of NLRs and genes encoding NLR-like proteins suggest that plant and animal NLRs have independently arisen in evolution. Furthermore, the demonstration of interfamily transfer of plant NLR functions from their original species to phylogenetically distant species implies evolutionary conservation of the underlying immune principle across plant taxonomy. In this review we discuss plant NLR evolution and summarize recent insights into plant NLR-signaling mechanisms, which might constitute evolutionarily conserved NLR-mediated immune mechanisms.

Keywords
NB-LRR NLR effector-triggered immunity innate immunity resistance protein
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Jacob Florence
Department of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research , Cologne , Germany ; Unité de Recherche en Génomique Végétale, Institut National de la Recherche Agronomique, Centre National de la Recherche Scientifique, Université Evry Val d'Essone , Evry , France.
Vernaldi Saskia
Maekawa Takaki
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Article Info
Journal
Frontiers in immunology
Abbr.
Front Immunol
ISSN
1664-3224
DOI
10.3389/fimmu.2013.00297
Published
2013-09-25
Epub
2013-00-25
Pages
297
Language
English
Region
Switzerland
NLM ID
101560960
PMCID
PMC3782705
External Links
PubMed source DOI: 10.3389/fimmu.2013.00297 PMC Full Text View journal details
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