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PMID: 1549509 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

Compilation and analysis of DNA sequences associated with apparent streptomycete promoters.

Nucleic acids research ·Vol. 20 ·No. 5 ·1992-03-11 ·Pages 961-74

Strohl WR

Abstract

The DNA sequences associated with 139 apparent streptomycete transcriptional start sites are compiled and compared. Of these, 29 promoters appeared to belong to a group which are similar to those recognized by eubacterial RNA polymerases containing sigma 70-like subunits. The other 110 putative promoter regions contain a wide diversity of sequences; several of these promoters have obvious sequence similarities in the -10 and/or -35 regions. The apparent Shine-Dalgarno regions of 44 streptomycete genes are also examined and compared. These were found to have a wide range of degree of complementarity to the 3' end of streptomycete 16S rRNA. Eleven streptomycete genes are described and compared in which transcription and translation are proposed to be initiated from the same or nearby nucleotide. An updated consensus sequence for the E sigma 70-like promoters is proposed and a potential group of promoter sequences containing guanine-rich -35 regions also is identified.

MeSH Terms
Actinomycetales/genetics Base Sequence Consensus Sequence/genetics Genes, Bacterial/genetics Molecular Sequence Data Promoter Regions, Genetic/genetics RNA, Ribosomal, 16S/genetics Streptomyces/genetics
Chemicals
RNA, Ribosomal, 16S
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Strohl W R
Department of Microbiology, Ohio State University, Columbus 43210.
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/20.5.961
Published
1992-03-11
Pages
961-74
Language
English
Region
England
NLM ID
0411011
PMCID
PMC312078
Subset
IM
Grants
NIGMS NIH HHS · GM-43345 · United States
External Links
PubMed source DOI: 10.1093/nar/20.5.961 PMC Full Text View journal details
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