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PMID: 8550093 Published · ppublish English Journal Article Review

Mouse T-cell receptor variable gene segment families.

Immunogenetics ·Vol. 42 ·No. 6 ·1995-00-00 ·Pages 501-30

Arden B, Clark SP, Kabelitz D, Mak TW

Abstract

All mouse T-cell receptor alpha/delta, beta, and gamma variable (Tcra/d-, b-, and g-V) gene segments were aligned to compare the sequences with one another, to group them into subfamilies, and to derive a name which complies with the standard nomenclature. It was necessary to change the names of some V gene segments because they conflicted with those of other segments. The traditional classification into subfamilies was re-evaluated using a much larger pool of sequences. In the mouse, most V gene segments can be grouped into subfamilies of closely related genes with significantly less similarity between different subfamilies.

MeSH Terms
Amino Acid Sequence Animals Base Sequence Mice Molecular Sequence Data Receptors, Antigen, T-Cell, alpha-beta/classification,genetics Receptors, Antigen, T-Cell, gamma-delta/classification,genetics Sequence Alignment Terminology as Topic
Chemicals
Receptors, Antigen, T-Cell, alpha-beta Receptors, Antigen, T-Cell, gamma-delta
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Arden B
Paul-Ehrlich-Institute, Langen, Germany.
Clark S P
Kabelitz D
Mak T W
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Article Info
Journal
Immunogenetics
Abbr.
Immunogenetics
ISSN
0093-7711
DOI
10.1007/BF00172177
Published
1995-00-00
Pages
501-30
Language
English
Region
United States
NLM ID
0420404
Subset
IM
Databases
GENBANK
M16675, M16676, M16678, M21202, M21857, M26423, M27352, M31647, M33586, M34194, M34196, M38104, M38678, M60999, M76612, X01133, X02833, X02857, X02928, X02929, X02931, X02932, X02969, X03669, X05187, X05732, X05733, X05734, X06771, X56701
External Links
PubMed source DOI: 10.1007/BF00172177 View journal details
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